Impact of hypnosis during coronarography

##plugins.themes.academic_pro.article.sidebar##

Published Jan 22, 2026
https://doi.org/10.62438/tunismed.v103i11.5890
Download
PDF
Vol. 103 No. 11 (2025): Tunis Med Nov 2025

##plugins.themes.academic_pro.article.main##

Hela Bouzidi
Cardiology department, Habib Thameur university hospital, Faculty of medicine of Tunis ,University of Tunis El Manar , Tunis, Tunisia
Selim Boudiche
Cardiology department, La Rabta university hospital, Faculty of medicine of Tunis ,University of Tunis El Manar , Tunis, Tunisia
Hakime Lamine
Cardiology department, La Rabta university hospital, Faculty of medicine of Tunis ,University of Tunis El Manar , Tunis, Tunisia
Bouthaina Besbes
Cardiology department, La Rabta university hospital, Faculty of medicine of Tunis ,University of Tunis El Manar , Tunis, Tunisia
Mohamed Sami Mourali
Cardiology department, La Rabta university hospital, Faculty of medicine of Tunis ,University of Tunis El Manar , Tunis, Tunisia

Abstract

Background: Although coronarography is common and relatively with low risk, patients may experience anxiety about the procedure and about the implications that some diagnosis may have. Hypnosis is an alternative technique with rising interest to prevent anxiety during this procedure.


Aim: The aim of this study is to better understand the effectiveness of hypnosis in reducing anxiety and discomfort in patients undergoing coronarography.


Methods : A total of 60 patients with nonemergency indication for coronarography were randomly divided into two groups: one control group (CTRL), and one experimental group of patients who underwent coronarography under hypnosis (HYP).


Results : Results of our study suggest that hypnosis reduces significantly anxiety. Average Visual analogue scale (VAS) score was significantly lower in HYP group (0.7 ± 0.47 vs 1.66 ± 0.9 in CTRL group, (P=0.037)). Average Verbal rating scale (VRS) score was also significantly lower in HYP group (0.23±0.13 vs 0.83 ±0.6 in CTRL group; (P=0.03)). Need for morphine hydrochloride infusion was significantly lower in HYP group compared to CTRL group (6.7% vs 30% p= 0.02). There was no difference in the occurrence of adverse events between the two groups. For the physician performing the coronarography, procedure quality was similar in both groups (P= 0.59), although right radial puncture was more successful in HYP group (one failure of right radial puncture (3.3%) versus 6 (20%) in the CTRL group (p =0.044)).


Conclusion :  Our results demonstrated a significant reduction of perceived ....(Abstrat truncated at 250 words)

Keywords:

Hypnosis, Coronary angiography, Anxiety, Pain, spasm

##plugins.themes.academic_pro.article.details##

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

References

  1. Gach O, Davin L, Lempereur M, Marechal P, Martinez C, Lancellotti P. Coronarographie diagnostique [Diagnostic coronarography]. Rev Med Liege. 2019 Sup;74(S1):S17-S21.
  2. Lang EV, Berbaum KS, Pauker SG, et al. Beneficial effects of hypnosis and adverse effects of empathic attention during per-cutaneous tumor treatment: when being nice does not suffice.JVascIntervRadiol 2008;19:897-905.
  3. Green JP, Barabasz AF, Barrett D, Montgomery GH. Forgingahead: the 2003 APA Division 30 definition of hypnosis. Int JClinExpHypn 2005;53:259-64.
  4. Baglini R, Sesana M, Capuano C, Gnecchi-Ruscone T, Ugo L, Danzi GB. Effect of hypnotic sedation during percutaneous transluminal coronary angioplasty on myocardial ischemia and cardiac sympathetic drive. Am J Cardiol. 2004;93(8):1035-8.
  5. Amedro P, Gavotto A, Gelibert D, Fraysse V, De La Villeon G, Vandenberghe D, Bredy C. Feasibility of clinical hypnosis for transesophageal echocardiography in children and adolescents. Eur J Cardiovasc Nurs. 2019;18(2):163-170.
  6. Elkins GR, Barabasz AF, Council JR, Spiegel D. Advancing research and practice: the revised APA Division 30 definition of hypnosis. Int J Clin ExpHypn. 2015;63:1-9.
  7. Spiegel D. Neurophysiological correlates of hypnosis and dissociation. J Neuropsychiatr Clin Neurosci. 1991;3:440–5.
  8. Julian, L. J. (2011). Measures of anxiety: State-Trait Anxiety Inventory (STAI), Beck Anxiety Inventory (BAI), and Hospital Anxiety and Depression Scale-Anxiety (HADS-A). Arthritis Care &Research, 63(S11), S467–S472.
  9. Delgado DA, Lambert BS, Boutris N, et al. Validation of Digital Visual Analog Scale Pain Scoring With a Traditional Paper-based Visual Analog Scale in Adults. J Am AcadOrthopSurgGlobRes Rev. 2018;2(3):e088.
  10. Haefeli, Mathias, and Achim Elfering. “Pain assessment.” European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society vol. 15 Suppl 1,Suppl 1 (2006): S17-24.
  11. likert R. A technique for the measurement of attitudes. Arch Psychology.1932;22(140):55.
  12. Bailey PL, Pace NL, Ashburn MA, Moll JW, East KA, Stanley TH.Frequent hypoxemia and apnea after sedation with midazolamand fentanyl. Anesthesiology 1990;73:826-30.
  13. Hızlı F, Özcan O, Selvi İ, et al. The effects of hypnotherapy during transrectal ultrasound-guided prostate needle biopsy for pain and anxiety. Int UrolNephrol. 2015;47(11):1773-1777.
  14. Lang EV, Berbaum KS, Faintuch S, et al. Adjunctive self-hypnotic relaxation for out patient medical procedures: a prospective randomized trial with women undergoing large core breast biopsy. Pain. 2006;126(1-3):155-164.
  15. Saadat H, Drummond-Lewis J, Maranets I, et al. Hypnosis reduces preoperative anxiety in adult patients. AnesthAnalg 2006;102(5):1394-1396.
  16. Laure Abensur V, Charles G, Sandrine W, Nadia O, Julien B, Mathieu V, et al.Effectiveness of Hypnosis for the Prevention of Anxiety During Coronary Angiography (HYPCOR study): a prospective randomized study.BMC Complement Med Ther 2022 Nov 29;22(1):315.
  17. Noble, C., F., Benedetti, E., D., Noble, S. (2011). 'Les coronarographies et les angioplasties coronaires par voie radiale : l’approche de choix ?', Rev Med Suisse 2011; volume -3. no. 285, 528-532.
  18. Faymonville ME, Mambourg PH, Joris J, et al. Psychological approaches during conscious sedation—hypnosis versus stress reducing strategies: a prospective randomized study. Pain 1997; 73: 361–67.
  19. Faymonville ME, Fissette J, Mambourg PH, et al. Hypnosis as adjunct in conscious sedation for plastic surgery. Reg Anesth 1995; 20: 145–51.
  20. Greenleaf M, Fisher S, Miaskowski C, DuHamel K. Hypnotizability and recovery from cardiac surgery. Am J Clin Hypn 1992;35(2):119–128.
  21. Dogan Y, Eren GA, Tulubas E, Oduncu V, Sahin A, Ciftci S. The effect of sedation during transesophageal echocardiography on heart rate variability: a comparison of hypnotic sedation with medical sedation. Kardiol Pol.
  22. Sletvold H, Jensen GM, Götestam KG. Blood pressure responses to hypnotic and nonhypnotic suggestions in normotensive subjects. Pavlov J Biol Sci. 1986;21(1):32-35.
  23. Grossman P, Watkins LL, Wilhelm FH, Manolakis D, Lown B. Cardiac vagal control and dynamic responses to psychological stress among patients with coronary artery disease. Am J Cardiol. 1996;78(12):1424-1427.
  24. Aubert AE, Verheyden B, Beckers F, Tack J, Vandenberghe J. Cardiac Autonomic Regulation under Hypnosis Assessed by Heart Rate Variability: Spectral Analysis and Fractal Complexity. Neuropsychobiology. 2009;60(2):104-112.
  25. Baglini R, Sesana M, Capuano C, Gnecchi-Ruscone T, Ugo L, Danzi GB. Effect of hypnotic sedation during percutaneous transluminal coronary angioplasty on myocardial ischemia and cardiac sympathetic drive. Am J Cardiol. 2004;93(8):1035-1038.
  26. GUEGUEN J, BARRY C, HASSLER C, FALISSARD B. Evaluation de L’efficacité de La Pratique de L’hypnose. Inserm U1178 Santé Mentale & Santé Publique; 2015.