Agenesis of the Dorsal Pancreas: An Uncommon Cause of Pancreatic Diabetes in Young Adults. A Case Report

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Published Feb 1, 2025
https://doi.org/10.62438/tunismed.v103i2.5405
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Vol. 103 No. 2 (2025): Tunis Med Feb 2025

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Yosra Hasni
Endocrinology department, Hospital Farhat Hached, Sousse. Ibn El Jazzar Faculty of Medical of Sousse, University of Sousse, Tunisia.
Wiem Saafi
Endocrinology department, Hospital Farhat Hached, Sousse. Ibn El Jazzar Faculty of Medical of Sousse, University of Sousse, Tunisia.
Hamza El Fekih
Endocrinology department, Hospital Farhat Hached, Sousse. Ibn El Jazzar Faculty of Medical of Sousse, University of Sousse, Tunisia.
Salem Braham
Radiology department, Hospital Farhat Hached Sousse, Tunisia
Soumaiya Tahri
Endocrinology department, Hospital Farhat Hached, Sousse. Ibn El Jazzar Faculty of Medical of Sousse, University of Sousse, Tunisia.
Amel Maaroufi
Endocrinology department, Hospital Farhat Hached, Sousse. Ibn El Jazzar Faculty of Medical of Sousse, University of Sousse, Tunisia.

Abstract

Introduction: Agenesis of the dorsal pancreas (ADP) is a rare congenital abnormality characterized by the absence of the body and tail of the pancreas. This condition is often asymptomatic. While many patients exhibit nonspecific symptoms, some may experience more severe manifestations complicating the diagnostic process.


Observation: We presented the case of a 27-year-old man who was diagnosed with type 1 diabetes mellitus three years ago. He was experiencing considerable weight loss, abdominal pain, and diarrhea despite effectively managed insulin therapy. The patient appeared emaciated and malnourished. Investigations revealed a normal thyroid function, negative celiac disease serology, and negative pancreatic antibodies. Abdominal imaging demonstrated ADP. After treatment with insulin and pancreatic enzymes, we noted a significant improvement in the patient's condition.


Conclusion: This case emphasizes diagnostic challenges in young patients presenting with pancreatic diabetes. Early recognition and appropriate management are crucial to prevent complications of both exocrine and endocrine deficiencies.

Keywords:

Congenital Abnormalities, Endocrine glands, Magnetic resonance imaging, Pancreas, Pancreatic diseases

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This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

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