Epistaxis in children with allergic rhinitis: Clinical features and risk factors depending on the allergen profile

##plugins.themes.academic_pro.article.main##

Amani Hachicha
Hamdi Chouchane
Houneida Boussafa
Senda Turki
Ferdaous Yangui
Ridha Charfi

Abstract

Introduction: Epistaxis in children is a very common reason for consultation in ENT and pediatric emergencies. Most of these epistaxis are benign, but it is their recurrence that motivates anxious parents, to consult. Allergic rhinitis is a common pathology among children in Tunisia, it seemed interesting to us to study the association between allergic rhinitis and epistaxis. 


Aim: Identify the clinical features and the risk factors for epistaxis in children with allergic rhinitis.


Methods: Retrospective descriptive cohort study over a period of 4 years, including children, who consulted for epistaxis at the ENT and CCF department of FSI Hospital, La Marsa Tunis. All cases were divided into 2 groups: ERA+ Group: epistaxis with allergic rhinitis versus ERA- Group: epistaxis without allergic rhinitis. 


Results: 79 children were included, including 21 (26.6%) meeting the diagnostic criteria for allergic rhinitis. A female predominance was noted in the ERA+ group. In the ERA+ group, epistaxis mainly occurred in summer and autumn (38% and 28%) while it predominated in winter and summer in the ERA- group. Rhinorrhea and nasal pruritus were factors significantly associated with epistaxis in children with allergic rhinitis. 


Conclusion: the ENT doctor must think about allergic rhinitis in case of Repetitive epistaxis in a child, and look for suggestive symptoms, particularly rhinorrhea and nasal prurit. 

Keywords:

epistaxis, allergic rhinitis, child

##plugins.themes.academic_pro.article.details##

References

  1. - Murray A, Milner R. Allergic rhinitis and recurrent epistaxis in children. Ann Allergy Asthma Immunol. 1995 Jan; 74(1):30-3.
  2. - Faistauer M, Faistauer Â, Rafaeli SG, Roithmann R. Clinical outcome of patients with epistaxis treated with nasal packing after hospital discharge. Braz J Otorhinolaryngol. 2009;75:857–65.
  3. - Brożek JL et al. Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines-2016 revision. J Allergy Clin Immunol. 2017 Oct;140(4):950-958.
  4. - Boscardini L, Zanetta S, Ballardini G, et al. Epistaxis in children under the age of two: possible marker of abuse/neglect? A retrospective study in North-Eastern Piedmont hospitals. Minerva Pediatr. 2013;65(01):71–75
  5. - Flora Y, Hetvi P et al. Age Distribution of Epistaxis in Outpatient Pediatric Patients. 2023 October(20)
  6. - Qing J, Cai Y, Tang S, Wang Y. Clinical Characteristics and Risk Factors for Allergic Rhinitis in Children with Epistaxis. Int J Clin Pract. 2023 Aug 31;2023:6731414.
  7. - Toujani S, Mjid M et al. Prevalence of asthma and rhinitis in a Tunisian population. Clin Respir J. 2018 Feb;12(2):608-615.
  8. - Mark S. Dykewicz et al. Rhinitis 2020: A practice parameter update et Epistaxis Risk Associated with Intranasal Corticosteroid Sprays: A Systematic Review and Meta-analysis Eric L. J Allergy Clin Immunol 2020 Oct;146(4):721-767.
  9. - ElAlfy MS et al. Epistaxis in a Pediatric Outpatient Clinic. Int Arch Otorhinolaryngol 2022;26(2):e183–e190.
  10. - Shieh A et al. Risk Factors and Management Outcomes in Pediatric Epistaxis at an Emergency Department. J Emerg Med 2024 Feb;66(2):97-108.
  11. - Erdogmus N et al. Can we determine recurrent epistaxis by hemogram parameters in children? Int J Pediatr Otorhinolaryngo . 2021 Jul:146:110747.
  12. - R. Purkey, Z. Seeskin, and R. Chandra, “Seasonal variation and predictors of epistaxis,” 8e Laryngoscope, vol. 124, no. 9, pp. 2028–2033, 2014.
  13. - Eun-Jin A, Hyun Jin M. Environmental factors differentially affect epistaxis among preschool and school-aged children Front Public Health. 2023 Aug; 11: 1178531.
  14. - Lu Y. X. et al. Pediatric epistaxis and its correlation between air pollutants
  15. in Beijing from 2014 to 2017. Ear, Nose and troat Journal 2020: 99(8), pp. 513– 517
  16. - M Montague. The pathology of visible blood vessels on the nasal septum in children with epistaxis. Int J Pediatr Otorhinolaryngol . 2011 Aug;75(8):1032-4.
  17. - Tyler Yan R. Recurrent epistaxis in children. Can Fam Physician. 2021 Jun;67(6):427-429
  18. - Amit K et al. Is Chemical Cauterization Safe on Septal Cartilage in Treatment of Recurrent Epistaxis? Indian J Otolaryngol Head Neck Surg 2022 October. 74(Suppl 2):S1322–S