Tuberculosis in southern Morocco: Retrospective analysis from 2006 to 2012

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Published May 12, 2024
https://doi.org/10.62438/tunismed.v102i5.4825
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Vol. 102 No. 5 (2024): Tunis med may 2024

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Nabil Ait Ouaaziz
Natural resources and sustainable development laboratory, department of biology. Faculty of science, University Ibn Tofail, Kenitra, Morocco.
Mohamed El Bakkali
Biology and health laboratory, department of biology. Faculty of sciences, Ibn Tofail University, Kenitra, Morocco
Ouafae El Yahyaoui
Natural resources and sustainable development laboratory, department of biology. Faculty of science, University Ibn Tofail, Kenitra, Morocco
Fadia Bejja
Biology and health laboratory, department of biology. Faculty of sciences, Ibn Tofail University, Kenitra, Morocco
Youness Taboz
Natural resources and sustainable development laboratory, department of biology. Faculty of science, University Ibn Tofail, Kenitra, Morocco.
Abd El Majid Soulaymani
Biology and health laboratory, department of biology. Faculty of sciences, Ibn Tofail University, Kenitra, Morocco
Ali Quyou
Natural resources and sustainable development laboratory, department of biology. Faculty of science, University Ibn Tofail, Kenitra, Morocco

Abstract

Introduction: Tuberculosis, a global major concern, causes millions of deaths annually despite WHO strategies. A persistent gap in detection and treatment facilitates rapid spread in high-burden countries.


Aims: Analyze the clinical-epidemiological profile of tuberculosis patients in Laayoune and Tarfaya, Morocco, emphasizing risk factors and evolution of the tuberculosis


Methods: Retrospective analysis of 1332 tuberculosis cases at the Respiratory Diseases Diagnosis and Treatment Center in Laayoune (2006-2012). Variables with P < 0.10 in univariate analysis were included in multivariate analysis using multiple logistic regression to define the risk factors for tuberculosis, expressed as odds ratios (OR) with a 95% confidence interval (CI).


Results: The analysis revealed a pulmonary predominance (≈61%), with pleural (41.3%) and lymph node (31.5%) tuberculosis prevalent among extrapulmonary cases. Among 515 extrapulmonary tuberculosis cases, intestinal tuberculosis (14 cases) showed the highest mortality rate at 14.29%. The 15 to 64 age groups had a significantly higher risk of contracting pulmonary tuberculosis to children, and the 65 and over age group also had the highest risk of developing pulmonary tuberculosis (aOR=5.83 [2.43, 14.00]). Other risk factors included rural origin, personal history of tuberculosis, and smoking, all significantly associated with pulmonary tuberculosis (aOR=2.40 [1.001, 5.76]; aOR=2.00 [1.11, 3.61]; aOR=2.38 [1.40, 4.06]). Conversely, female gender was a protective factor (aOR=0.53 [0.40, 0.70]). Regarding recovery and loss to follow-up rates, they were higher in those with pulmonary tuberculosis (39.0% vs 2.1%; aOR=33.41 [17, 66.52]; 16.9% vs 10.3%; aOR=1.57 [1.02, 2.41], respectively).


Conclusion: Holistic initiatives across various ...( abstract truncated at 250 words).

Keywords:

Morocco, mortality, risk factors, Laayoune

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