Vitamin Status of Obese Tunisian adults before and after Sleeve Gastrectomy

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Published Nov 6, 2023
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Vol. 101 No. 8-9 (2023): Tunis med aug-sept 2023

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Faten Mahjoub
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia
Sarra Khlifi
Research Obesity Unit , National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis- University of Tunis El Manar, Tunis, Tunisia.
Rim Rachdi
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia
Nadia Ben Amor
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia
Ramla Mizouri
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia
Marwa Omri
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia
Henda Jamoussi
Department A, National Institute of Nutrition and Food Technology of Tunis, Faculty of Medicine of Tunis,University of Tunis El Manar, Tunisia

Abstract

Introduction: The worldwide obesity epidemic continues unabated. Obesity and its associated health risks are considered as the major causes of morbidity and mortality. Currently, bariatric surgery is the most effective treatment for people with severe obesity resulting in sustainable weight loss and a reduced risk for co-morbidities. Sleeve gastrectomy is the most common bariatric procedure undertaken in Tunisia.


Aim: we aim to evaluate the vitamin status of the obese patients before and after sleeve gastrectomy.


Methods: Thirty obese patients undergoing sleeve gastrectomy, were recruited from Obesity unit. In this study. A biological assessment was performed pre-operatively and controlled 6 months following the sleeve gastrectomy including: calcemia, parathyroid hormone (PTH), albuminemia and dosage of vitamin D, vitamin B9 and vitamin B12. 


Results: Six months post sleeve gastrectomy, vitamin deficiencies were more prevalent: the mean level of vitamin B9, vitamin B12 and vitamin D respectively, has decreased from 5.03±3.28 ng / ml to 2.71±1.52 ng / ml, from 348.06±158.92 pg/ml to 264.62±119.77 pg/ml and from 17.18±11.45 ng/ml to 11.69±8.22 ng/ml, with a statistically significant difference (p=0.008, p=0.01 and p=0.012). Sleeve gastrectomy has proven to be an effective weight loss treatment. However, nutritional deficiencies have worsened during postoperative period.


Conclusion: This study highlights the importance of early identification, appropriate treatment and prophylactic micronutrient supplementation.

Keywords:

Obesity, Sleeve gastrectomy, Vitamin D, Vitamin B9, Vitamin B12, Nutritional deficiencies

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