Cribriform plate dehiscence with encephalomeningocele revealed by recurrent meningitis: a case report

##plugins.themes.academic_pro.article.main##

Najla Soyah
Hajer Ben Belgacem
Donia Brahem
Nadia Mama
Raoudha Kebaili
Samia Tilouche
Marwa Abdelberi
Nesrine Jaballah
Jihene Bouguila
Lamia Boughamoura

Abstract

Introduction. Meningitis is a potentially life threatening illness. It requires prompt diagnosis and treatment. Recurrent meningitis needs detailed investigations to identify the underlying cause.


Observation. We report a case of recurrent pneumococcal meningitis in a 9-year-old boy with an underlying congenital skull base abnormality. Brain computed tomography (CT) scan showed no obvious skull base defects. A magnetic resonance imaging (MRI) of the brain revealed a dehiscence of the cribriform plate with encephalomeningocele. The patient underwent an endoscopic repair of the bony defect and had not developed any new infections ever since.


Conclusion. This case highlights the need to investigate recurrent bacterial meningitis with CT scan and MRI of the brain and skull base. Repair of these congenital skull base defects are mandatory to prevent the recurrence of meningitis.

Keywords:

Cribliform plate dehiscence, Encephalomeningocele, Recurrent meningitis

##plugins.themes.academic_pro.article.details##

References

  1. Sfaihi L, Kamoun F, Kamoun T, Alloulou H, Mezghani S, Hammemi A, et al. Bacterial meningitis in children: Epidemiological data and outcome. La Tunisie médicale. 2014;141‑6.
  2. Alsaeed G, Alsaeed I, Alsaeed M. Recurrent Bacterial Meningitis in Paediatrics. American Journal of Pediatrics. 2019;5 (3):98.
  3. Masri A, Alassaf A, Khuri-Bulos N, Zaq I, Hadidy A, Bakri FG. Recurrent meningitis in children: etiologies, outcome, and lessons to learn. Child's Nervous System. 2018; 34(8):1541‑7.
  4. Tebruegge M, Curtis N. Epidemiology, etiology, pathogenesis, and diagnosis of recurrent bacterial meningitis. Clinical Microbiology Reviews. 2008; 21(3):519‑37.
  5. Janocha-Litwin J, Simon K. Recurrent meningitis--a review of current literature. Przeglad Epidemiologiczny. 2013; 67(1):41‑5, 125‑9.
  6. Ter Horst L, Brouwer MC, van der Ende A, van de Beek D. Recurrent Community-Acquired Bacterial Meningitis in Adults. Clinical Infectious Disease 2021; 73(9):e2545‑51.
  7. Tuygun N, Tanir G, Aytekin C. Recurrent bacterial meningitis in children: our experience with 14 cases. The Turkish Journal Pediatrics. 2010; 52(4):348‑53.
  8. Tracy A, Waterfield T. How to use clinical signs of meningitis. Archives of Disease in Childhood Education and Practice Edition.2020;105 (1):46‑9.
  9. Bektas D, Caylan R, Bahadir O, Caylan R. Occult anterior skull base defect without rhinorrhea as a cause of recurrent meningitis. Surgical Neurology. 2007; 68(1):50‑2.
  10. Li X, Liu HZ, Pang L yu, Wen X, Sun SZ. A Retrospective Study of Recurrent Bacterial Meningitis in Children: Etiology, Clinical Course, and Treatment. Computational and Mathematical Methods in Medecine. 2022; 2022: 3681871.
  11. Morgenstern Isaak A, Bach Faig A, Martínez S, Martín-Nalda A, Vázquez Méndez E, Pumarola Segura F. et al Recurrent meningitis due to anatomical defects : The bacteria indicates its origin. Anal of Pediatria. 2015; 82(6):388‑96.
  12. Lee E, Yum MS. Recurrent Bacterial Meningitis in Pediatric Patients with Anatomical Defects. Annals of child neurology.2011;19(2):101-107
  13. Rosenberg J, Galen BT. Recurrent Meningitis. Current Pain and Headache Reports. 2017; 21(7):33.
  14. Dewan R, Anuradh S, Garg S, Kochhar R, Negi M, Nischal N. Encephalcoele- A Cause of Recurrent Meningitis. jk sciences. 2015; 17(1):54-56.
  15. Masuoka S, Miyazaki O, Takahashi H, Tsutsumi Y, Hiyama T, Kitamura M, et al. Predisposing conditions for bacterial meningitis in children: what radiologists need to know. Japanese Journal of Radiology. 2022;40 (1):1‑18.
  16. Carrol ED, Latif AH, Misbah SA, Flood TJ, Abinun M, Clark JE, et al. Recurrent bacterial meningitis: the need for sensitive imaging. The BMJ. 2001; 323(7311):501‑3.
  17. Akimoto T, Morita A, Shiobara K, Hara M, Minami M, Shijo K, et al. Surgically Cured, Relapsed Pneumococcal Meningitis Due to Bone Defects, Non-invasively Identified by Three-dimensional Multi-detector Computed Tomography. Internal Medicine. 2016; 55(24):3665‑9.
  18. Hiremath SB, Gautam AA, Sasindran V, Therakathu J, Benjamin G. Cerebrospinal fluid rhinorrhea and otorrhea: A multimodality imaging approach. Diagnostic and Interventional Imaging. 2019; 100(1):3‑15.
  19. Wilson M, Snyderman C. Endoscopic Management of Developmental Anomalies of the Skull Base. Journal of Neurological Surgery. 2018; 79(1):13‑20.
  20. Mantravadi AV, Welch KC. Repair of Cerebrospinal Fluid Leak and Encephalocele of the Cribriform Plate. Atlas of Endoscopic Sinus and Skull Base Surgery. 2019. 223-232.
  21. Adriani KS, van de Beek D, Brouwer MC, Spanjaard L, de Gans J. Community-acquired recurrent bacterial meningitis in adults. Clinical Infectious Disease .2007;45(5):46-51.
  22. van de Beek D, Brouwer M, Hasbun R, Koedel U, Whitney CG, Wijdicks E. Community-acquired bacterial meningitis. Nature Review Disease Primer. 2016;(2):16074.
  23. Ter Horst L, Brouwer MC, van der Ende A, van de Beek D. Community-acquired Bacterial Meningitis in Adults With Cerebrospinal Fluid Leakage. Clinical Infectious Diseases. 2020;70 (11):2256‑61.
  24. Rimmer J, Belk C, Lund VJ, Swift A, White P. Immunisations and antibiotics in patients with anterior skull base cerebrospinal fluid leaks. The Journal of Laryngology Otology. 2014; 128(7):626‑9
  25. Ratilal BO, Costa J, Pappamikail L, Sampaio C. Antibiotic prophylaxis for preventing meningitis in patients with basilar skull fractures. Cochrane Database Systimic Review. 2015;(4):CD004884.