Risk factors for acquiring BMR infections: Analytical study

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Published Mar 10, 2024
https://doi.org/10.62438/tunismed.v102i3.4578
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Vol. 102 No. 3 (2024): Tunis med mar 2024

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Nabila Kalla
Faculty of Medicine of Batna, University of Batna, Algeria
Ouanassa Hamouda
Faculty of Medicine of Batna, University of Batna, Algeria
Lina Noui
Faculty of Medicine of Batna, University of Batna, Algeria
Amani Melizi
Faculty of Medicine of Batna, University of Batna, Algeria
Souhila Aouidane
Faculty of Medicine of Batna, University of Batna, Algeria
Zohra Merzougui
Faculty of Medicine of Batna, University of Batna, Algeria

Abstract

Introduction: In recent years, there has been a considerable increase in the prevalence of bacteria increasingly resistant to multiple families of antibiotics, which constitutes a major problem for public health.


Aim: To determine the prevalence and different risk factors for the acquisition of multi-resistant bacteria.


Methods: This is an analytical and prospective study including patients hospitalized in the Batna University Hospital during the period from January 2023 to March 2023 presenting a documented infection with isolation of sensitive or multi-resistant strains. An operating sheet based on the different risk factors for acquiring multi-resistant bacteria has been established.


Results: We collected 250 patients. There are 160 men and 90 women with an average age of 44 years. Of all the strains that were identified, 100 isolates were multi-resistant bacteria. ESBL-producing Enterobacteriaceae are the most frequently isolated multi-resistant bacteria. Multivariate logistic regression analysis identified four risk factors that are significantly related to the risk of acquiring multi-resistant bacteria infection: prior antibiotic therapy [P = 0,029], use of invasive medical care [P = 0,024], the nosocomial origin of the infection [P = 0,036] and the use of public toilets [P = 0,015].


Conclusion: Our results clearly demonstrate that the inappropriate use of antibiotics, especially broad-spectrum antibiotics, and hand-held cross-transmission play a major role in the spread of multi-resistant bacteria in our hospital.

Keywords:

multi-resistant bacteria, Prevalence, Risk factors, Acquisition

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