Explanatory factors for the evolution of children’s allergic rhinitis

##plugins.themes.academic_pro.article.sidebar##

Published May 12, 2024
https://doi.org/10.62438/tunismed.v102i5.4463
Download
PDF
Vol. 102 No. 5 (2024): Tunis med may 2024

##plugins.themes.academic_pro.article.main##

Senda Turki
Department of Otorhinolaryngology and cervico-facial surgery. Internal Security Forces Hospital, La Marsa ,Tunis, Tunisia
Souheil Jbali
Department of Otolaryngology and Cervico-facial Surgery, Salah Azaiez Institute, Tunis, Tunisia
Amani Hachicha
Department of Otolaryngology and Cervico-facial Surgery, Internal Security Forces Hospital, La Marsa, Tunis, Tunisia
Hamdi Chouchane
Department of Otolaryngology and Cervico-facial Surgery, Internal Security Forces Hospital, La Marsa, Tunis, Tunisia
Aymen Sifaoui
Department of Otolaryngology and Cervico-facial Surgery, Salah Azaiez Institute, Tunis, Tunisia
Mohamed Ridha Charfi
Department of Pneumology, Internal Security Forces Hospital, La Marsa, Tunis, Tunisia

Abstract

Introduction: Allergic rhinitis (AR) in children is a common condition that is a public health problem. Despite a well-codified treatment, clinical improvement is not the rule.


Aim: To identify factors affecting the improvement of allergic rhinitis in children under symptomatic treatment.


Methods: A 12-year retrospective descriptive study that included children aged 3 to 15 years, followed for allergic rhinitis. The search for explanatory factors for improvement under treatment was done using a binary logistic regression model.


Results: 52 children were included, with a mean age of 7 years (±3). A familial atopy history was present in 37 patients (71%). The presence of factors aggravating allergy was noted, including antibiotic consumption: 31 patients (60%) and overweight: 15 patients (29%). Associated asthma was noted in 42 patients (81%). The allergenic profile has regained a predominance of dust mite allergy (71%) and a significant frequency of multiallergies (79%). Management included therapeutic education and drug treatment. There was improvement in rhinitis in 27 patients (52%) and improvement in asthma in 26 patients (50%). Overweight and high consumption of antibiotics had a negative impact on the therapeutic outcome. A good therapeutic education had a favorable impact.


Conclusion: AR is a debilitating condition requiring prolonged therapeutic education and drug treatment. The prescription of antibiotics in children with allergic rhinitis should be sparing and weight monitored.

Keywords:

allergy, rhinitis, asthma, children, treatment, quality of life

##plugins.themes.academic_pro.article.details##

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

References

  1. Société française d’oto-rhino-laryngologie et de la chirurgie de la face et du cou, éditeur. Rhinites allergiques: rapport 2019 de la Société française d’ORL et de chirurgie cervico-faciale. Issy-les-Moulineaux: Elsevier Masson; 2019. (Rapport de la Société française d’ORL et de chirurgie cervico-faciale).
  2. Raja Hannachi. Rhinite de l’enfant: profil allergique [Mémoire de fin d’études]. [tunis]: tunis el manar; 2018.
  3. Pr Louis Crampette . Pr Michel Justin. Recommandations pour la pratique clinique: Prise en charge diagnostique et thérapeutique des Rhinites Allergiques par l’ORL (hors rhinites professionnelles). 2020;
  4. Montoro J, Del Cuvillo A, Mullol J, Molina X, Bartra J, Dávila I, et al. Validation of the modified allergic rhinitis and its impact on asthma (ARIA) severity classification in allergic rhinitis children: the PEDRIAL study. Allergy. nov 2012;67(11):1437‑42.
  5. Demoly P, Bousquet PJ, Mesbah K, Bousquet J, Devillier P. Visual analogue scale in patients treated for allergic rhinitis: an observational prospective study in primary care: asthma and rhinitis. Clin Exp Allergy. août 2013;43(8):881‑8.
  6. Lezmi G, Karila C, De Blic J, Scheinmann P. Rhinite allergique de l’enfant : un phénotype à risque de persistance à l’âge adulte. Revue Française d’Allergologie. avr 2013;53(3):270‑4.
  7. Wise SK, Damask C, Roland LT, Ebert C, Levy JM, Lin S, et al. International consensus statement on allergy and rhinology: Allergic rhinitis – 2023. Int Forum Allergy Rhinol. avr 2023;13(4):293‑859.
  8. Abou Taam R, de Blic J, Scheinmann P. Rhinite allergique chez l’enfant. Revue Française d’Allergologie et d’Immunologie Clinique. sept 2008;48(5):394‑8.
  9. Morin A, McKennan CG, Pedersen CET, Stokholm J, Chawes BL, Malby Schoos AM, et al. Epigenetic landscape links upper airway microbiota in infancy with allergic rhinitis at 6 years of age. J Allergy Clin Immunol. déc 2020;146(6):1358‑66.
  10. Dastoorpoor M, Khodadadi N, Madadizadeh F, Raji H, Shahidizadeh E, Idani E, et al. Assessing the prevalence and severity of asthma, rhinitis, and eczema among schoolchildren (6-7 and 13-14 years old) in Khuzestan, Iran: a cross-sectional survey. BMC Pediatr. 2 août 2022;22(1):463.
  11. Blanquart E, Laffont S, Guéry JC. Effets protecteurs de la puberté chez les garçons dans les maladies allergiques : les androgènes un régulateur négatif des cellules lymphoïdes innées de groupe 2. Revue Française d’Allergologie. juin 2018;58(4):324‑30.
  12. Brindisi G, Marazzato M, Brunetti F, De Castro G, Loffredo L, Carnevale R, et al. Allergic rhinitis, microbiota and passive smoke in children: A pilot study. Pediatr Allergy Immunol. janv 2022;33 Suppl 27(Suppl 27):22‑6.
  13. Labbé G, Egron C, Labbé A. Le tabagisme passif chez l’enfant et les risques allergiques. Revue Française d’Allergologie. oct 2020;60(6‑7):540‑6.
  14. Casset A, Braun JJ. Relation entre allergènes de l’environnement intérieur, sensibilisation et symptômes de rhinite et asthme allergiques. Revue Française d’Allergologie. mars 2011;51(2):104‑10.
  15. D’Elia C, Gozal D, Bruni O, Goudouris E, Meira E Cruz M. Allergic rhinitis and sleep disorders in children - coexistence and reciprocal interactions. J Pediatr (Rio J). 2022;98(5):444‑54.
  16. Ma Y, Tang J, Wen Y, Hu Y, Liang J, Jiang L, et al. Associations of sleep problems with asthma and allergic rhinitis among Chinese preschoolers. Sci Rep. 16 mai 2022;12(1):8102.
  17. Feng MC, Tsai YG, Chang YH, Kuo CH, Lin YC, Hung CH. Allergic rhinitis as a key factor for the development of gastroesophageal reflux disease in children. Journal of Microbiology, Immunology and Infection. déc 2021;54(6):1167‑74.
  18. Lin YC, Chen YC, Kuo CH, Chang YH, Huang HY, Yeh WJ, et al. Antibiotic exposure and asthma development in children with allergic rhinitis. J Microbiol Immunol Infect. oct 2020;53(5):803‑11.
  19. Wang X, Tan X, Zhou J. Effectiveness and safety of probiotic therapy for pediatric allergic rhinitis management: A systematic review and meta-analysis. Int J Pediatr Otorhinolaryngol. nov 2022;162:111300.
  20. Tajima H, Pawankar R. Obesity and adiposity indicators in asthma and allergic rhinitis in children. Current Opinion in Allergy & Clinical Immunology. févr 2019;19(1):7‑11.
  21. Zhou J, Luo F, Han Y, Lou H, Tang X, Zhang L. Obesity/overweight and risk of allergic rhinitis: A meta-analysis of observational studies. Allergy. mai 2020;75(5):1272‑5.
  22. Dutau G, Lavaud F. La rhinite allergique et ses comorbidités. Revue Française d’Allergologie. 1 févr 2019;59(1):32‑40.
  23. Schuler IV CF, Montejo JM. Allergic Rhinitis in Children and Adolescents. Immunology and Allergy Clinics of North America. nov 2021;41(4):613‑25.