Oral manifestations of Behçet’s disease

##plugins.themes.academic_pro.article.main##

Mehdi Khemiss
Souhir Hajjaj
Ikdam Blouza
Maher Beji

Abstract

Introduction: Behçet’s disease is a chronic vasulitis. The aphtous stomatitis is present in nearly the totality of patients having this disease.

Aim: The purpose of this study was to evaluate the oral health of Behcet’s disease (BD) patients and then compare it with healthy controls.

Methods : Twenty patients with BD and 20 healthy subjects were included in this cross-sectional study conducted at the military hospital of
Bizerta from 01/10/2017 to 31/05/2019. The level of plaque were recorded using the plaque index (PI). The gingival index (GI) was used to
evaluate the gingival inflammation. The depths of the sulci/pockets were probed with a periodontal probe. The clinical attachment loss (CAL)
was measured from the cementoenamel junction to the sulcus base. The caries status was scored by using DMFT introduced by Klein and
Palmer.The diagnosis of oral lesions was performed using the visual tactile examination.

Results : The two groups were age, sexe, and socioeconomic level matched. The percentage of oral ulcers was observed to be higher in BD patients
compared with healthy controls (40% Vs 5%, p<0.01). Statistical significant differences in the two groups’ PI (1,19±0,38 Vs 0,86±0,37 ; p=0,011) and
GI (1,10±0,30 Vs 0,75±0,36 ; p=0,03) were observed. The probing depth, the CAL and the DMF/T showed no associations with the BD.

Conclusion : Our results showed that gingival health is worse in BD patients. Therfore, the dentist must play an important part in the
management of BD and the motivation for the oral hygiene.

##plugins.themes.academic_pro.article.details##

References

  1. Andaloussi IB, Alami B, Abdellaoui M, Bhallil S, Bono W, Tahri H. Les manifestations ophtalmologiques de la maladie de Behçet, à propos de 33 cas. Pan Afr Med 2012;13:1-12.
  2. B’chir Hamzaoui S, Harmel A, Bouslema K et al. Behçet’s disease in Tunisia. A clinical study of 519 cases. Rev Med Interne 2006;27(10):742-50.
  3. Mahr A, Maldini C. Épidémiologie de la maladie de Behçet. Rev Med Interne 2014;35(2):81-95.
  4. Lawton G, Bhakta BB, Chamberlain MA, Tennant A. The Behçet’s disease activity index. Rhumatology 2004;43(1):73-8.
  5. Yazici H. The place of Behçet’s syndrome among the autoimmune diseases. Int Rev Immunol 1997;14:1-10.
  6. Alpsoy E, Donmez L, Bacanli A, Apaydin C, Butun B. Review of the chronology of clinical manifestations in 60 patients with Behçet’s disease. Dermatology 2003;207(4):354-6.
  7. Bulur I, Onder M. Behçet disease : New aspects. Clin Dermatol 2017;35(5):421-34.
  8. International Team for the revision of the international criteria for Behçet’s disease (ITR-ICBD). The international criteria for Behçet’s Disease (ICBD): a collaborative study of 27 countries on the sensitivity and specificity of the new criteria. J Eur Acad Dermatol Venerol 2014; 28(3): 338-47.
  9. Vaillant L, Samimi M. Aphtes et ulcérations buccales. Presse Med 2016;45(2):215-26.
  10. Kang M, Ragan BG, Park JH. Issues in outcomes research : an overview of randomization techniques for clinical trials. J Athl Train 2008;43(2):215-21.
  11. B’chirHamzaoui S, Larbi T, Abdallah M et al. La maladie de Behçet au maghreb. Etude Behçet Maghreb : à propos de 1460 patients. Rev Med Interne 2010;31:252.
  12. Institut national de la statistique et des études économiques. Guide des catégories socioprofessionnelles. Paris: INSEE, 1993.
  13. Loe H, Silness J. Periodontal disease in pregnancy I. Prevalence and severity. Acta Odontol Scand 1963;21:533-51.
  14. Klein H, Palmer CE. Studies dental caries: a procedure for recording and statistical proceeding of dental examination findings. J Dent Res 1940;19:243-52.
  15. Silness J, Loe H. Periodontal disease in pregnancy II. Correlation between oral hygiene and periodontal condition. Acta Odontol Scand 1964;22:121-35.
  16. Fleszar TJ, Knowles JW, Morrison EC, Burgett FG, Nissle RR, Ramfjord SP. Teeth mobility and periodontal therapy. J ClinPeriodontol 1980;7(6):495-505.
  17. Akman A, Ekinci NC, Kacaroglu H, Yavuzer U, Alpsoy E, Yegin O. Relationship between periodontal findings and specific polymorphisms of interleukin-I alpha and interleukin-I beta in Turkish patients with Behçet’s disease. Arch Dermatol Res 2008;300(1):19-26.
  18. Akman A, Kacaroglu H, Donmez L, Bacanli A, Alpsoy E. Relationship between periodontal findings and Behcet’s disease: a controlled study. J Clin Periodontal 2007;34(6):485-91.
  19. Miura H, Isogai E, Mizugai H, Miura K. Perceived oral health status, oral function and related behavior among the patients of Behçet disease. Asia Pas J Public health 2000;12(2):98-101.
  20. Mizushima Y, Matsuda T, Hoshi K, Ohno S. Induction of Behcet’s disease symptoms after dental treatment and streptococcal antigen skin test. J Rheumatol 1988;15(6):1029-30.
  21. Arabaci T, Kara C, Cicek Y. Relationship between periodontal parameters and Behçet’s disease and evaluation of different treatments for oral recurrent aphthous stomatitis. J Periodont Res 2009;44(6):718-25.
  22. Cacoub P, Vallet H. Actualités de la maladie de Behçet. Real TherDermato-Venerol 2014;324(1):24-7.
  23. Haskard DO, Ambrose NL. Differential diagnosis and management of Behçet syndrome. Nat Rev Rheum 2013;9(2):79.
  24. Amoura Z, Guillaume M, Caillat-Zucman S, Wechsler B, Piette JC. Physiopathologie de la maladie de Behçet. Rev Med Interne 2006;27(11):843-53.
  25. Celenligil-Nazliel H, Kansu E, Ebersol JL. Periodontal findings and systemic antibody response to oral microorganism in Behçet disease. J Periodontal 1999;70(12):1449-56.
  26. Habibagahi Z, Khorshidi H, Hekmati S. Periodontal health status among patients with Behçet’s disease. Scientifica (cairo) 2016;2016:7506041.
  27. Mumcu G, Inanc N, Ergun T et al. Oral health related quality of life is affected by disease activity in Behçet’s disease. Oral disease 2006;12:145-51.
  28. Mann CJ. Observational research methods. Research design II: cohort, cross sectional, and case-control studies. Emerg Med J 2003;20(1):54-60.