What is the interest of the electroencephalogram in the syndromic diagnosis?

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Ines Kammoun
Héla Mnif
Fatma Kamoun Feki
Kaouthar Masmoudi
Chahnez Triki

Abstract

Introduction:The identification of the epileptic syndrome is a challenge particularly in childhood epilepsies. In fact, the diagnosis may need several years to be fulfilled. Observation:Our patient presented at the age of 3 years 6 months atypical absence. His electroencephalogram (EEG) showed generalized spikes and waves andpolyspikes and waves. At age 6, he has developed other types of seizures: slow fall of the head, shoulders jerks,slow fall to the side and loss of consciousness. All these phenomena were organized in a fortuitous and variable association from one period to another over 2 years. Meanwhile, the child developed cognitive impairment. EEG showed fast rhythms in sleep and waking. It was only at the age of 8years, whenthe child developedtonic seizures,that we made the diagnosis of Lennox-Gastaut syndrome.
Conclusion: In the absence of Specific Markers, syndromic diagnosis in epilepsy remains Electro- clinical.


Keywords:

Lennox Gastautsyndrome, myoclono-astatiques seizures, electroencephalogram, tonic seizures

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References

  1. Pina-Garza JE, Chung S, Montouris GD, Radtke RA, Resnick T, Weschler RT. Challenges in identifying Lennox-Gastaut syndrome in adults: A case series illustrating its changing nature. Epilepsy Behav Case Rep 2016; 11; 5: 38-43. DOI: 10.1016/j.ebcr.2016.01.004. eCollection 2016.
  2. Kaminska A, Oguni H. Lennox-Gastaut syndrome and epilepsy with myoclonic-astatic seizures.HandbClinNeurol 2013;111:641-52. DOI: 10.1016/B978-0-444-52891-9.00067-1
  3. Kelley SA, Kossoff EH. Doose syndrome (myoclonic-astatic epilepsy): 40 years of progress. Dev Med Child Neurol 2010; 52; 11:988-93. DOI: 10.1111/j.1469-8749.2010.03744.x. Epub 2010 Aug 16.
  4. Arzimanoglou A1, Resnick T.All children who experience epileptic falls do not necessarily have Lennox-Gastaut syndrome... but many do.EpilepticDisord 2011; 13; 1:S3-13. DOI: 10.1684/epd.2011.0422.
  5. Bourgeois BF, Douglass LM, Sankar R. Lennox-Gastaut syndrome: A consensus approach to differential diagnosis. Epilepsia 2014; 55; 4:4-9.DOI: 10.1111/epi.12567.
  6. Plouin P, Kaminska A, Moutard ML et Soufflet C. Livre L'EEG en pédiatrie, Paris 2005 :98.