Factors associated with poor medication compliance in hypertensive patients

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Published Sep 17, 2018
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Vol. 96 No. 6 (2018): Issue Jun 2018

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Khadija Mzoughi
Ihsen Zairi
Aymen Jemai
Mouna Ben Kilani
Hayfa Ben Daamar
Emna Ben Gaied Hassine
Sondos Kraiem

Abstract

Introduction: Hypertension is a major cause of cardiovascular morbidity and mortality. Despite therapeutic advances, only one-third of patients achieve blood pressure targets. Poor compliance is one of the main causes. The aim of our work was to study the factors associated with poor compliance in hypertensive patients.
Methods: We conducted a descriptive prospective study including 200 hypertensive patients treated and followed out between March and April 2017. The Girerd medication adherence questionnaire was submitted to patients during an semi-directed interview.
Results: Patients meanagewas of 63.28 ± 9.62 years-old and sex ratio of 0.92. The predominant risk factor was dyslipidemia in 45% of cases, followed by smoking 36.5% and diabetes 25.5%. A previous history of acute coronary syndrome was found in 33.5% of cases and atrial fibrillation in 13%. Fifteen percent of our patients consumed alcohol regularly and 9.5% practiced regular physical activity. Fifty-five percent of our patients were on low sodium diet. The prevalence of poor medication adherence was 20.5%.
In multivariate analysis, independent factors related to poor medication adherence were: the number of treating specialist physicians greater than 1 (OR = 3.444, p = 0.008) and the absence of information received on hypertension (OR = 4.345; p= 0.003).
Conclusion:The improvement of medication adherence for our patients must be based on information on hypertension and its risks and the harmonization of care between treating physicians.

Keywords:

Hypertension- Treatment- therapeutic compliance

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