unicentric castleman’s disease: an uncommon cause of chronic cough

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Published Sep 3, 2018
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Vol. 96 No. 2 (2018): Issue Feb 2018

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Saoussen Bacha
Hazem Zribi
Sonia Habibech
Monia Attia
Aida Ayadi
Faouzi Mezni
Abdellatif Chabbou

Abstract

Abstract:
Castleman disease (CD) or angiofollicular lymph node hyperplasia is a rare lymphoproliferativedisorder characterized by lymph node hyperplasia of uncertain etiology. CD is divided clinically into unicentric (localized to one region of the body) considered as a benign disease andmulticentric with less favourableprognosis. We describe a case of intrathoracicunicentricCD revealed by a chronic non-productive cough in a 50-year-oldnon-smoker female. Chest computed tomography revealed a bulky right hilar mass with intense homogenous contrast enhancement. The patient underwent a right upper lobectomy and mediastinal lymphadenectomy. Histopathology was consistent with hyaline-vascular (HV) type CD. The patient remained asymptomatic throughout the subsequent 6-months of follow-up.

Keywords:

Castleman disease; intrathoracic; unicentric; angiofollicular lymph node hyperplasia; chronic cough

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