Sociodemographic and obstetric features of the patients followed in a protocol of prevention of the mother-child transmission of the HIV1 in the Sylvanus Olympio teaching hospital

##plugins.themes.academic_pro.article.sidebar##

Published May 10, 2018
Download
pdf
Vol. 95 No. 12 (2017): Issue Dec 2017

##plugins.themes.academic_pro.article.main##

Takassi Ounoo Elom
Salou Mounérou
Fiawoo Mawouto
Guédénon Koffi
Akpadja Koffi
Atakouma Yawo

Abstract

Introduction:Preventing mother-to-child transmission (PMTCT) of HIV decreases new HIV infections in children. The objectives of our study were to describe the sociodemographic and obstetric characteristics of the patients of a protocol for the PMTCT of HIV-1 in Sylvanus Olympio Teaching Hospital.
Methods: We conducted a prospective cross-sectional descriptive study of the follow-up cohort type in the PMTCT siteof Sylvanus Olympio Teaching Hospital. It extended from 27 June 2011 to 27 May 2015.
Results: A total of 255 women were included. The average age of our patients was 30 years old with extremes of 18 and 45 years old. Resellers were 38.8% and housewives accounted for 17.6%. 48.2% of our patients had completed high school. Single persons accounted for 36.1% and 54.5% were married monogamous. Sixty-four percent of the patients were HIV-positive during pregnancy and 80.7% were in WHO clinical stage I. Only 17.3% of the patients had consulted the first time in the first trimester of pregnancy.
Conclusion: The results of this study reveal that the majority of our patients were young, asymptomatic and were mostly screened in our maternity ward.

Keywords:

HIV, PMTCT, Togo.

##plugins.themes.academic_pro.article.details##

References

  1. The Working Group on Mother-To-Child Transmission of HIV. Rates of mother-to-child transmission of HIV-1 in Africa, America, and Europe: results from 13 perinatal studies. J Acquir Immune DeficSyndr Hum Retrovirol1995; 8(5):506-10.
  2. European Collaborative Study. Mother-to-child transmission of HIV infection in the era of highly active antiretroviral therapy. Clin Infect Dis2005; 40(3):458-65.
  3. European Collaborative Study. The mother-to-child HIV transmission epidemic in Europe: evolving in the East and established in the West. AIDS 2006; 20: 1419-27.
  4. ONUSIDA. Rapport sur l'épidémie mondial de sida en 2013, Genève, ONUSIDA/JC2502/1/F
  5. CNLS IST Togo. Rapport d'activités de la réponse nationale contre le VIH et le Sida en 2013, Lomé CNLS IST. Togo 2013, p 62.
  6. Chama CM, Morrupa JY. The safety of elective caesarean section for the prevention ofmother-to-child transmission of HIV-1. Journalof Obstetrics and Gynaecology, 2008; 28(2):194 -97.
  7. Thomas TK, Masaba R, Borkowf CB, et al. Triple-Antiretroviral Prophylaxis to Prevent Mother-To-Child HIV Transmission through Breastfeeding—The Kisumu Breastfeeding Study, Kenya: A Clinical Trial. PLoS med 2011; 8 (3): e1001015.
  8. Ngemu EK, Khayeka-Wandabwa C, Kweka EJ, et al. Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women. BMC Research Notes 2014; 7:52. DOI:10.1186/1756-0500-7-52.
  9. Onah HE, Obi SN, Agbata TA, et al.Pregnancy outcome in HIV-positive women in Enugu, Nigeria. Journal of Obstetrics and Gynecology, April 2007; 27(3): 271 - 74.
  10. Alvarez-uria G, Midde M, Pakam R, et al. Effect of Formula Feeding and Breastfeeding on Child Growth, Infant Mortality, and HIV Transmission in Children Born to HIV-Infected Pregnant Women Who Received Triple Antiretroviral Therapy in a Resource-Limited Setting: Data from an HIV Cohort Study in India .ISNR pediatrics 2012; 20:1-9.
  11. Toumala RE, Shapiro DE, Moffenson CM. Antiretroviral therapy during pregnancy and the risk of adverse outcome. N Eng J Med2002; 346:1863-70.
  12. Dabis F, Bequet, Ekouevi DK, et al.Study Group. Field efficacy of zidovudine, lamivudine, and single-dose nevirapineto prevent peripartum HIV transmission. J Acquir Immune DeficSyndr2005; 19(3): 309-18.
  13. Rodriguez EJ, Spann C, Jamieson D, et al. Postoperative morbidity associated with cesarean delivery among human immunodeficiency virus-seropositive women.Am J ObstetGyneco2001; 184 (6):1108-11.
  14. Sebitloane HM, Moodley J, Tonya M, et al.Determinants of postpartum infectious complications among HIV uninfected and antiretroviral naive-HIV infected women following vaginal delivery: A prospective cohort study. European Journal of Obstetrics & Gynecology and Reproductive Biology 2009; 145: 158-62.
  15. Ticconi C, Mapfumo M, Dorrucci M, et al.Effect of maternal HIV and malaria infection on pregnancy and perinatal outcome in Zimbabwe. J Acquir Immune DeficSyndr. 2003 ; 34 : 289-94.