Agressive infection following a dental extraction in a diabetic patient :Rhinocerebral mucormycosis

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Alia Zehani
Ines Smichi
Jihene Marrakchi
Ghazi Besbes
Slim Haouet
Nidhameddine Kchir

Abstract

Mucormycosis is a rare and acute fungal infection which is frequently lethal, usually observed in non-controlled diabetic patients. The infection usually begins in the nose but it can invade the lung, the digestive tract, and the skin. Rhinocerebral mucormycosis accounts for 40 to 49% of mucormycosis cases. We report the case of a 44-year-old diabetic man, presenting with rhinocerebral mucormycosis. Our patient was treated by an association of amphotericin B and surgical debridement.

Keywords:

mucormycosis, rhinocerebral, diabetes

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References

  1. Gutiérrez-Delgado EM, Treviño-González JL, Montemayor-Alatorre A, Ceceñas-Falcón LA, Ruiz-Holguín E, Andrade-Vázquez CJ el al. Chronic rhino-orbito-cerebral mucormycosis: A case report and review of the literature. Ann Med Surg (Lond). 2016; 6:87-91.
  2. Zeddinia A, Meknia A, Ferchichia L. et al. Mucormycose rhinocerebrale: a propos d'un cas. Med Mal Infect. 2006; 36: 517-519.
  3. Spellberg B, Edwards Jr J, Ibrahim A. Novel perspectives on mucormycosis: pathophysiology, presentation and management. Clin Microbiol Rev. 2005;18:556-69.
  4. Cherif R, Ben Ali A, Gastli M, Chaker E, Daoud A. Zygomycose (mucormycose) rhino-orbito-cerebrale avec diabete insipide. Ann Fr Anesth Reanim. 1995; 14:41-4.
  5. Glockner A, Vehreschild JJ, Cornely OA. Zygomycosis: current epidemiological aspects. Mycoses 2007; 50(1):50-5. Talmi YP, Goldschmied-Reouven A., Bakon M. et al. Rhino-orbital and rhinoorbito-cerebral mucormycosis. Otolaryngol Head Neck Surg. 2002; 127:22-31.
  6. Charfi S, Ayadi L, Makni S. et al. Mucormycose rhinocerebrale : étude anatomoclinique de sept cas. J Mycol Med. 2008 ; 18 : 46-52.
  7. Leitner C, Hoffmann J, Zerfowski M, Reinert S. Mucormycosis: necrotizing soft tissue lesion of the face. J Oral Maxillofac Surg 2003; 61(11):1354-8.
  8. Carton S, Garson S, Benhaim T. et al Mucormycose cutanee primaire: a propos d'un cas. Ann Chir Plast Esthet. 2008; 53:368-371.
  9. Guevara N, Roy D, Dutruc-Rosset C, Santini J, Hofman P, Castillo L. Mucormycose - diagnostic précoce et traitement. Rev Laryngol Otol Rhinol(Bord). 2004; 125:127-31.
  10. Yohai RA, Bullock JD, Aziz AA, Markert RJ. Survival factors in rhino-orbitalcerebral Mucormycosis