Le score PNI permet de prédire la mortalité et la morbidité après chirurgie pour cancer de l’estomac

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Publiée Dec 7, 2016
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Vol. 94 No 7 (2016): Revue juil. 2016

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Mehdi Khalfallah
Hichem Jerraya
Akram Sbai
Wejih Dougaz
Amel Changuel
Ramzi Nouira
Ibtissem Bouasker
Chadli Dziri

Résumé

Abstract:
Introduction: The Prognostic Nutritional Index (PNI) score is based on the level of lymphocytes and albuminemia. The aim of this study was to validate the pre-operative PNI score for predicting post-operative mortality and morbidity of patients operated on for gastric cancer.
Methods: This retrospective study collected data from patients operated on for a gastric cancer at the surgical unit B of Charles Nicolle’s hospital in Tunis between January 1st, 2008 and December 31, 2012. The main outcome measure was post-operative death within 30 days. The secondary outcome was post-operative morbidity (within 30 days). We have performed a descriptive analysis, a univariate and multivariate analysis with logistic regression and a ROC curve analysis.
Results: 14 women and 26 men were enrolled, with a sex ratio of 1,85. The mean age was                         63 ± 15.  Post-operative mortality and morbidity rate were respectively 18% and 28%. The ROC curve allowed us to validate the PNI for predicting post-operative mortality in gastric cancer with a threshold level of 38 with sensitivity 100% and specificity 64%. PNI was also validated for post-operative morbidity with a threshold level of 38 with sensitivity 82% and specificity 66%.
Conclusion: PNI was validated for predicting post-operative mortality and post-operative morbidity in gastric cancer

Mots-clés :

gastric cancer, surgery, morbidity, mortality, prognostic nutritional index

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