CYTOLOGY AND IMMUNOPHENOTYPE FEATURES OF HAIRY CELL LEUKEAMIA : ABOUT 6 CASES

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Vol. 86 No. 2 (2008): Issue Feb 2008

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Emna Gouider
Service d'Hématologie Biologique Hôpital Aziza Othmana Tunis Tunisie
Naouel Ben Salah
Service d'Hématologie Biologique Hôpital Aziza Othmana Tunis Tunisie
Wijden El Borgi
Service d'Hématologie Biologique Hôpital Aziza Othmana Tunis Tunisie
Raouf Hafsia
Service d'Hématologie Biologique Hôpital Aziza Othmana Tunis Tunisie

Abstract

Background : Hairy cell leukemia is a rare lymphoproliferative disorder.
Aim : with cytological and immunophenotypic features.
Methods : We report 6 cases of hairy cell leukemia diagnosed in the Biological Department of Hematology at the Aziza Othmana Hospital of Tunis.
Results : Hairy cells was observed in blood smears of 5 cases. Flow cytometry analysis shown monoclonal a monoclonal population B while gatinting on the expression of the CD19 and SSC signal. The positivity of the CD103 is noted in 5 cases and the CD11c signal is intense in all the cases.
Conclusion : Immunophenotype is of great interest in the diagnosis of hairy cell leukemia.

Keywords:

Hairy cell leukemia, Flow cytometry, Monoclonal antibodies, Hairy cell, CD103, CD11c

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