Predictive factors of failure and mortality after CT-Guided percutaneous drainage of infected pancreatic necrosis.

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Published Jul 20, 2016
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Vol. 94 No. 1 (2016): Issue Jan 2016

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Wejih Dougaz
Ibtissem Bouasker
Samia Ben Osman
Ramzi Nouira
Chadli Dziri

Abstract

Background: The traditional approach to the drainage of infected pancreatic necrosis (IPN) is open necrosectomy. As an alternative to open necrosectomy, percutaneous drainage is the first-line treatment of IPN.
This study is aimed to identify predictive factor of failure after CT-guided percutaneous catheter drainage (PCD) of IPN.
Methods: Between June 1st 1988 and October 31th 2011, 26 patients with IPN were treated by PCD. The outcome measures were the failure of the PCD and/or death. A descriptive analysis was performed followed by a comparative analysis of alive versus deceased patients and success group versus failure group. Univariate and multivariate analysis were performed to determine predictive factors of failure after percutaneous drainage or death.
Results: The failure and mortality rates were respectively 38% and 34%. The size of catheter inferior to 10 French was the only variable associated with the percutaneous drainage failure (OR=27, CI95% [2.5-284.6], p=0.006]. The collection number on CT scan was associated with mortality (OR=2.2, IC95% [1-5.1], p=0.050).
Conclusion: PCD with catheter size equal or greater than 10 French is efficient tool for the treatment of IPN. Collection number on CT scan is an independent predictive factor of mortality.

Keywords:

Acute pancreatitis, Infection, Necrosis, Percutaneous drainage

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