Multicentric tubulopapillary carcinoma of the kidney associated with renal adenomatosis

##plugins.themes.academic_pro.article.main##

Aïda Ayadi-Kaddour
Abdelfattah Zeddeni
Emna Braham
Olfa Ismail
Faouzi El Mezni

Abstract

Tubulopapillary tumors of the kidney represent a particular group of the renal tumors. They cover a continuous spectrum of tumors ranging from the adenoma to the renal cells papillary carcinoma. The histological and immunohistochemical similarities, as well as the high recurrence of the association of these two entities suggest a continuity of the same biological process. Although rare, the association between adenoma and papillary carcinoma remains still subject to controversy and plead in favor of a narrow relation between them. We report the case of a multicentric tubulopapillary carcinoma of the kidney associated with multifocal adenomas, discovered by fortuity in a right nephrectomy at a 57-year-old patient operated for an obstructive chronic pyelonephritis.

Keywords:

Kidney - Tubulopapillary carcinoma - Papillary adenoma - Adenomatosis.

##plugins.themes.academic_pro.article.details##

References

  1. Combes F, Saidi A, Delaporte V, Lechevallier E, André M, Daniel L et al. Tubulopapillary tumours of the kidney: prognostic value and therapeutic implications of the distinction between type 1 and type 2 based on a series of 58 cases. Prog Urol 2005; 15:1062-9
  2. Eble JN, Epstein JI, Sesterhenn IA. Pathology and Genetics. Tumours of the urinary system and male genital organs. Lyon, France; IARC Press; 2004
  3. Lager DJ, Huston B.J, Timmerman TG. Papillary renal tumours: morphologic, cytochemical and genotypic features. Cancer 199;76 : 669-73
  4. Kiyoshima K, Oda Y, Nakamura T, Migita T, Okumura K, Naito S, Tsuneyoshi M. Multicentric papillary renal cell carcinoma associated with renal adenomatosis. Pathol Int. 2004; 54: 266-72.
  5. Wang KL, Weinrach DM, Luan C. Renal papillary adenoma. A putative precursor of papillary renal cell carcinoma. Hum Pathol 2007;38:239-46
  6. Zhou M, Yang XJ, Lopez JI, Shah RB, Hes O, Shen SS, et al. Renal tubulocystic carcinoma is closely related to papillary renal cell carcinoma: implications for pathologic classification. Am J Surg Pathol. 2009; 33 :1840-9.