Quality of life during menstruation in women with an inherited bleeding disorder: A 31 cases study

##plugins.themes.academic_pro.article.sidebar##

Published Dec 10, 2012
Download
pdf
Vol. 90 No. 12 (2012): Issue Dec 2012

##plugins.themes.academic_pro.article.main##

Anis Fadhlaoui
Mohamed Khrouf
Amel Chelbi
Kaouther Zahra
Emna Gouider
Fethi Zhioua
Anis Chaker
Balkis Meddeb

Abstract

Background: Menstruations, by their abundance and their duration, can be a source of impaired quality of life. Women with inherited bleeding disorders appear to be, specially at risk.
Aim: Assess the impact of menstrual blood loss on the quality of life for women with inherited bleeding disorders.
Methods: 31 women with various inherited bleeding disorders were interviewed. They completed a quality of life questionnaire.
Results: Von Willebrand disease was the most frequent inherited bleeding disorder in our population (38.7%). 54.8% of patients had a menstrual period more than 6 days 61.3% of them consider their menstrual flow to be normal. The general condition apart of the menstrual period was considered medium to poor in 35.5% of patients. The average score assessing the impact of menstruation on daily life was of 5.00 ± 3.47. Only 19.35% of patients felt that dysmenorrhea significantly affect their quality of life. Impaired quality of life was seen in 64.5% of patients according to score Aand in 41.9% of them according to score B. During menstruation 22.6% of the patients didn’t do to work or to school because of the menstrual flow. On the other hand, 48.4% of patients were hospitalized at least once for a heavy menstrual flow.
Conclusion: The quality of life during menstruation, in women with an inherited bleeding disorder, according to the different scores appear altered. Although because of the small size of our study population, we could not prove correlation between the importance of menstrual blood loss and the impairment of quality of life.

Keywords:

Inherited bleeding disorder, menorrhagia, dysmenorrhea, quality of life

##plugins.themes.academic_pro.article.details##

References

  1. Morcel K, Guerrier D, Watrin T, Pellerin I, Levêque J. Le syndrome de Mayer-Rokitansky-Küster-Hauser (MRKH) : clinique et génétique. J Gynecol Obstet Biol Reprod 2008; 1016: 88-90.
  2. Azoury RS, Jones Jr HW. Cytogenetic findings in patients with congenital absence of the vagina. Am J Obstet Gynecol 1966;94:178-80.
  3. Sarto GE. Cytogenetics of fifty patients with primary amenorrhea. Am J Obstet Gynecol 1974;119:14-23.
  4. Folch M, Pigem I, Konje JC. Mullerian agenesis: etiology, diagnosis, and management. Obstet Gynecol Surv 2000;55:644- 49.
  5. Griffin JE, Edwards C, Madden JD, Harrod MJ, Wilson JD. Congenital absence of the vagina. The Mayer-Rokitansky-Kuster- Hauser syndrome. Ann Intern Med 1976;85:224-236.
  6. Carson SA, Simpson JL, Malinak LR, et al. Heritable aspects of uterine anomalies. Genetic analysis of Mullerian aplasia. Fertil Steril 1983;40: 86-90.
  7. Klingele CJ, Gebhart JB, Croak AJ, DiMarco CS, Lesnick TG, Lee RA. McIndoe procedure for vaginal agenesis: long-term outcome and effect on quality of life. Am J Obstet Gynecol 2003;189:1569-72.
  8. Hojsgaard A, Villadsen I. McIndoe procedure for congenital vaginal agenesis: complications and results. Br J Plast Surg 1995;48:97-102.
  9. Sensoz O, Kocer U, Percin AK. Treatment of vaginal agenesis with modified Abbe-McIndoe technique. Eur J Plast Surg 1995;18: 285-7.
  10. Borruto F, Chasen ST, Chervenak FA, Fedele L. The Vechietti procedure for surgical treatment of vaginal agenesis: comparison of laparoscopy and laparotomy. Int J Gynecol Obstet 1999;64:153-8.
  11. Fedele L, Frontino G, Restelli E, et al. Creation of a neovagina by Davydov's laparoscopic modified technique in patients with Rokitansky syndrome. Am J Obstet Gynecol 2010; 202:33.e1-6.
  12. Giannesi A, Marchiole P, Benchaib M, Chevret-Measson M, Mathevet P, Dargent D. Sexuality after laparoscopic Davydov in patients affected by congenital complete vaginal agenesis associated with uterine agenesis or hypoplasia. Hum Reprod 2005;20:2954-7.
  13. Soong YK, Chang FH, Lee CL, Lai YM. Vaginal agenesis treated by laparoscopically assisted neovaginoplasty. Gynecol Endosc 1994;3:217-20.
  14. Fedele L, Bianchi S, Zanconato G, Raffaelli R. Laparoscopic creation of neovagina in patients with Rokitanky syndrome: analysis of 52 cases. Fertil Steril 2000;74:384-9.
  15. Fedele L. Creation of a neovagina in Rokitansky patients with a pelvic kidney: comparison of long-term results of the modified Vecchietti and McIndoe techniques. Fertility and Sterility 2009; 20: 87-90.
  16. F. Borruto, F.S. Camoglio, N. Zampieri, L. Fedele, The laparoscopic Vecchietti technique for vaginal agenesis . International Federation of Gynecology and Obstetrics 2007 ; 900-2.
  17. Alessandrescu D, Peltecu GC, Buhimschi CS, Buhimschi IA. Neocolpopoiesis with split-thickness skin graft as a surgical treatment of vaginal agenesis: retrospective review of 201 cases. Am J Obstet Gynecol 1996;175:131-8.
  18. Hojsgaard A, Villadsen I. McIndoe procedure for congenital vaginal agenesis: complications and results. Br J Plast Surg 1995;48:97-102.
  19. Adamyan LV. Laparoscopic management of vaginal aplasia with or without functional noncommunicating rudimentary uterus. In: Arrequi F, Kathouda, Mckerman, Reich, editors. Principles of laparoscopic surgery. NewYork: Springer-Verlag 1995; 646-51.
  20. Soong Y-K, Chang F-H, Lai Y-M, Lee C-L, Chou H-H. Results of modified laparoscopically assisted neovaginoplasty in 18 patients with congenital absence of vagina. Hum Reprod 1996;11:200-3.
  21. Rosen R, Brown C, Heiman J, et al. The Female Sexual Fuction Index (FSFI): a multidimensional selfreport instrument for the assessment of female sexual function. J Sex Marital Ther 2000;26:191-208.
  22. Communal PH, Chevret-Measson M, Golfier F, Raudrant D. Sexuality after sigmoid colpopoiesis in patients with Mayer- Rokitansky-Kuster- Hauser Syndrome. Fertil Steril 2003;80:600- 6.
  23. Brun JL, Belleannee G, Grafeille N, Aslan AF, Brun GH. Longterm results after neovagina creation in Mayer-Rokitanski- Kuster-Hauser syndrome by Vecchietti's operation. Eur J Obstet Gynecol Reprod Biol 2002;103:168-72.