Coronary artery bypass grafting in diabetic patients: Early and mid-term outcomes

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Published Nov 23, 2012
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Vol. 90 No. 11 (2012): Issue Nov 2012

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Habib Ben Ahmed
Mehdi Chelli
Khalifa Selmi
Khaled Bouzouita
Imen Hamdi
Aida Mokaddem
Youssef Ben Ameur
Mohamed R Boujnah

Abstract

Background: The outcome of coronary artery bypass grafting (CABG) in diabetic patients has traditionally been worse than in nondiabetic patients. Recent studies have suggested an improvement in outcome in diabetic patients undergoing CABG. However, the direct impact of diabetes on mortality and morbidities following CABG remains unclear.
Aim: To evaluate the early and mid term outcomes of diabetic patients compared to non-diabetics following CABG.
Methods: We retrospectively analyzed the data of 228 CABG patients from January 2005 to December 2010: one hundred and twenty-six diabetics and 102 non-diabetic.Diabetic patients were more likely to be female(27% Vs 12.7% P=0.009) were less smoker (55.6% Vs 80.4% P<0.0001) with higher rate of three vessel disease(67.5% Vs 42.2% P=0.005) compared to non-diabetics.
Results: Hospital mortality was significantly higher among diabetic patients (16% Vs 4.1% P=0.005).Length of care unit stay was more important (2.3 days Vs 2.1 days P=0.048) , but with a similar rate of sternal wound infection even after bilateral internal thoracic artery grafting. After 28 months mean follow- up, mid-term survival of diabetics was significantly decreased compared to no-diabetics (91% Vs 99% p<0.001) .However, Event-free survival was similar in the two groups (76% Vs 80% p=0.82).
Conclusion: These results suggest that diabetes is associated with poorer early and mid-term outcomes following (CABG).

Keywords:

Coronary artery bypass grafting , diabetes.

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