Epidemiological changes of paediatric urolithiasis in Tunisia
##plugins.themes.academic_pro.article.main##
Abstract
Background: The clinical and biological characteristics of urolithiasis in children are still evolving in our country. Since the eighties no study has been conducted to determine incidence of urolithiasis in Tunisia.
Aim: To define the current status of urolithiasis inTunisian children.
Methods: The records of 414 children with urolithiasis treated between 1983 and 2007 were found in a multi-centric study which took into consideration to age, sex, and history diagnosis and physical, laboratory, and radiologic findings. Clinical and biological date were performed in 344 cases. Stone analysis was performed by spectrophotometry.
Results: The incidence of paediatric urolithiasis has steadly decreased from 0.7/ 10 000 of the child population / year in 1991-1994 to 0.1 cases/10 000 children/ year in 2007. There was a continuous decrease in bladder stone over the past 25 years (47.1% in 1982-1986 Vs 10.2% in 2002-2007). Stones were homogeneous in 31.4% of cases. The main component was calcium oxalate stones in 36.4% of the cases. Since the eighties the increase of oxalates stones (15.6% in eighties Vs 51.5% actually) were with depends to purines and struvite stones.
Conclusion: Epidemiologic characteristics of the urinary lithiasis (sex, age, localization and composition) have changed in Tunisia, due to the the improvements of standard of living. The occidentalization of the nutritional practices and the receding of the culinary traditions gave birth to new risks of urolithiasis characterized by the emergence of calcium oxalate stones.
Aim: To define the current status of urolithiasis inTunisian children.
Methods: The records of 414 children with urolithiasis treated between 1983 and 2007 were found in a multi-centric study which took into consideration to age, sex, and history diagnosis and physical, laboratory, and radiologic findings. Clinical and biological date were performed in 344 cases. Stone analysis was performed by spectrophotometry.
Results: The incidence of paediatric urolithiasis has steadly decreased from 0.7/ 10 000 of the child population / year in 1991-1994 to 0.1 cases/10 000 children/ year in 2007. There was a continuous decrease in bladder stone over the past 25 years (47.1% in 1982-1986 Vs 10.2% in 2002-2007). Stones were homogeneous in 31.4% of cases. The main component was calcium oxalate stones in 36.4% of the cases. Since the eighties the increase of oxalates stones (15.6% in eighties Vs 51.5% actually) were with depends to purines and struvite stones.
Conclusion: Epidemiologic characteristics of the urinary lithiasis (sex, age, localization and composition) have changed in Tunisia, due to the the improvements of standard of living. The occidentalization of the nutritional practices and the receding of the culinary traditions gave birth to new risks of urolithiasis characterized by the emergence of calcium oxalate stones.
Keywords:
Urolithiasis, child, evolution, epidemiology, Tunisia##plugins.themes.academic_pro.article.details##
References
- Nahlovsky J, Farhat M, Gharbi S. Fréquence extraordinaire de la lithiase chez les enfants en Tunisie et leurs causes probables. J Urol Néphrol 1969 ; 75 : 539-41.
- Kamoun A, Daudon M, Abdelmoula J et al. Urolithiasis in Tunisian children: a study of 120 cases based on stone composition. Pediatr Nephrol 1999; 13: 920-25.
- Kamoun A, Zghal A, Daudon M et al. La lithiase urinaire de l'enfant : contributions de l'anamnèse, de l'exploration biologique et de l'analyse physique des calculs au diagnostic étiologique. Arch Pédiatr 1997 ; 4: 629-45.
- Najjar Mf, Najjar F, Boukef K, Ouelati A, Memmi J, Bechraoui T. La lithiase infantile dans la région de Monastir étude clinique et biologique. Le Biologiste 1986; 165 : 31-39.
- Joual A, Rais H, Rabil R, El Mrin M, Benjelloun S. Epidémiologie de la lithiase urinaire. Ann Urol 1997; 31: 80-3.
- Alaya A, Nouri A, Najjar MF. Paediatric renal stone disease in Tunisia: A 12 years experience. Arch Ita Urol Androl 2008; 80: 1-6.
- INS. Recensement général de la population et de l'habitat Données sur la Population et l'habitat 2004. 28 Avril 2004.www.ins.nat.tn
- Robertson Wg, Walker Vr, Hughes H, Husain I, Faqih SR. Renal stone disease in the Middle East. In : Hatano M. Nephrology. Vol 1. Tokyo; Springer-Verlag 1991.p. 815-22.
- Rizvi Sa, Naqvi SA, Hussain Z, Shahjehan S. Renal stones in children in Pakistan. Br J Urol 1985; 57: 618-21.
- Srivastava Rn, Hussainy Maa, Goel RG, Rose GA. Bladder Stone disease in children in Afghanistan. Br J Urol 1986; 58: 374-77.
- Dajani Am, Abu Khadra Al Baghdadi FM. Urolithiasis in Jordanian children. A report of 52 cases. Br J l Urol 1988; 61:482-86.
- 1Coward Rjm, Peters Cj, Duffy PG et al. Epidemiology of paediatric renal stone disease in the UK. Arch Dis Child 2003; 88: 962-65.
- Daudon M, Amiel J. Epidémiologie de la lithiase. Prog Urol 1999; 9: 5-16.
- Cachat F, Barbey F, Guignard JP. Epidémiologie de la lithiase urinaire chez l'enfant. Rev Med Suisse Romande 2004; 124: 433-37.
- Sternberg K, Grennfield Sp, Williot P, Wan J. Pediatric stone disease: an evolving experience. J Urol 2005; 174: 1711-14.
- Erbarci A, Erbarci Ab, Yilmaz M et al. Pediatric Urolithiasis. Evaluation of Risk Factors in 95 Children. Scand J Urol Nephrol 2003; 37: 129-33.
- Sarkissian A, Babloyan A, Arikiants N, Hesse A, Blau N, Leumann E. Pediatric urolithiasis in Armenia: a study of 198 patients observed from 1991 to 1999. Pediatr Nephrol 2001; 16:728-32.
- Daudon M, Bounxouei B, Santa Cruz F et al. Composition des calculs observés aujourd'hui dans les pays non industrialisés. Prog Urol 2004 ; 14: 1151-61.
- Angwafo Ff, Daudon M, Wonkam A, Kuwong Pm, Kropp KA. Pediatric urolithiasis in sub-saharian Africa: A comparative study in two regions of Cameroon. Eur Urol 2000; 37: 106-11.
- Hassan I, Mabogunie OA. Urinary stones in children in Zaria. Ann Tropical Paediatrics 1993; 13:269-71.
- Ali Sh, Rifat UN. Etiological and clinical patterns of childhood urolithiasis in Iraq. Pediatr Nephrol 2005; 20:1453-57.
- Al-Aisa Aa, Al-Hunayyan A, Gupta R. Pediatric urolithisis in Kuwait. Int Urol Nephrol 2002; 33: 3-6.
- Al- Rasheed Sa, El-Faqih Sr, Husain I, Abdurrahman M, Al- Mugeirin MM. The aetiological and clinical pattern of childhood urolithiasis in Saudi Arabia. Int Urol Nephrol, 1995; 27: 349-55.
- Harrache D, Mesri Z, Addou A, Semmoud A, Lacour B, Daudon M. La lithiase urinaire chez l'enfant dans l'ouest algérien. Ann Urol 1997 ; 31 : 84-5.
- Oussama A, Kzaiber F, Mernari B, Semmoud A, Daudon M. Analyse de la lithiase de l'enfant dans le moyen Atlas Marocain par spectrométrie infrarouge. Ann Urol 2000 ; 34 : 384-90.
- Kamoun A, Daudon M, Kabaar N, et al. Facteurs étiologiques de la lithiase urinaire de l'enfant en Tunisie. Prog Urol 1995 ; 5:942-5.
- Daudon M. L'analyse morphoconstitutionnelle des calculs dans le diagnostic étiologique d'une lithiase urinaire de l'enfant. Arch Pédiatr 2000; 7 : 855-65.
- Ben Romdhane H, Khaldi R, Oueslati A, Skhiri H. Transition épidémiologique et transition alimentaire et nutritionnelle en Tunisie. Options Méditerranéennes 2002; 41:7-27.
- Anderson DA. Historical and geographical differences in the pattern of incidence of urinary stones considered in relation to possible aetiological factors. In: Hodgkinson A, Nordin BEC, eds, Renal stone research symposium. London: Churchill, 1969; 7-31.
- Anderson DA. Environmental factors in the aetiology of urolithiasis. In: Cifuentes Delatte L, Rapado A, Hodgkinson A, eds, Urinary calculi. Recent advances in aetiology, stone structure and treatment. Basel: Karger, 1973; 130-144.