Is there a link between the occurrence of Kidney cancer and hypertension in Tunisian population?

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Published May 10, 2012
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Vol. 90 No. 5 (2012): Issue May 2012

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Ferchichi Imen
Nadia. Kourda
Derouiche Amine
Baltagi Sarra
Mohamed Chebil
Amel Benammar-Elgaaied

Abstract

Background: Kidney cancer is generally asymptomatic and discovered incidentally at a late stage, which is a negative diagnosis because in most cases the disease is incurable at this stage. Some predisposing factors have been revealed by studies such high blood pressure, which is a frequent among the Tunisian population.
Aim: A study among the Tunisian population to determine if there is a link between the occurrence of kidney cancer and the hypertension.
Methods: Our work was conducted on 91 patients with confirmed renal cell carcinoma and 91 healthy subjects who consulted the Urology Department at the Charles Nicolle Hospital in Tunis. The study of clinical records has identified the clinical, pathological and therapeutic features of the 182 patients.
Results: 59% of individuals with hypertension have developed kidney cancer with a significant p-value equal to 0.03. The more the value of blood pressure increases the more the risk is (p = 0.03). Smoking in combination with hypertension is a factor favoring the occurrence of cancer with a value of p equal to 0.05.
Conclusion: In the Tunisian population hypertension is a risk factor for developing kidney cancer, a factor compounded by the high incidence of this disease. What prompts us to make explorations of kidney lodges of hypertensive patients.

Keywords:

Hypertension; kidney cancer; risk factor

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