Cutaneous schwannoma: Study of 26 cases

##plugins.themes.academic_pro.article.sidebar##

Published Dec 19, 2011
Download
pdf
Vol. 89 No. (2011): Issue Dec 2011

##plugins.themes.academic_pro.article.main##

Talel Badri
Houda Hammami
Wafa Koubaa
Rym Benmously
Salima Ben Jennet
Sana Said
Aschraf Debbiche
Inçaf Mokhtar
Samy Fenniche

Abstract

Background: Schwannoma is generally a benign tumour developing from Schwann cells.
Aim: To study epidemiological, clinical and pathological features of scwannoma.
Methods: Retrospective study about 26 cases of cutaneous schwannoma collected in our department over 24 years.
Results: Our patients were 12 females and 14 males. Mean age was 30 years. Clinically, schwannoma was a subcutaneous tumour which was painful in 11 cases. Individual tumours were located on the limbs (10 cases), on the head (9 cases) and the trunk (5 cases). Multiple tumours were seen in two patients. Histopathological examination confirmed the diagnosis of schwannoma in all cases. Treatment was complete surgical excision in all cases.
Conclusion: Cutaneous location of schwannoma is not rare. Usually, and contrarily to our series, there is no sex predominance. Clinically, schwannoma is located on the limbs and head. The diagnosis is confirmed by histopathological examination. Malignant epitheloid schwannoma diagnosed in one of our patients is a rare tumour. Schwannomas usually grow slowly and are poorly invasive. Malignant degeneration is exceptional. Treatment is complete surgical excision.

Keywords:

Schwannoma, skin, tumour

##plugins.themes.academic_pro.article.details##

References

  1. Kumagai M, Endo S, Shiba K, et al. Schwannoma of the retropharyngeal space. Tohoku J Exp Med 2006; 210:161-4.
  2. Berrada R., Chahtane A, Lakhdar A, et al. Schwannome malin du sein. J Gynecol Obstet Biol Reprod 1998;27: 441-4.
  3. Dhouib M, Briki S, Ben Mahfoudh K, et al. Schwannome mélanocytique de la région temporozygomatique. Rev Stomatol Chir Maxillofac 2007;108:139-42.
  4. Knight DM, Birch R, Pringle J. Benign solitary schwannomas. J Bone Joint Surg Br 2007;89:382-7.
  5. Traistaru R, Enachescu V, Manuc D, Gruia C, Ghilusi M. Multiple right schwannoma. Rom J Morphol Embryol 2008;49: 235-9.
  6. Kurtkaya-Yupicier Ö, Schneithauer B, Woodruff JM. The pathobiologic spectrum of schwannomas. Histol Histopathol 2003;18:925-34.
  7. Berg JC, Scheithauer BW, Spinner RJ, Allen CM, Koutlas IG. Plexiform schwannoma. Hum Pathol 2008;39:633-40.
  8. Koeppel MC, Andrac-Meyer L. Tumeurs conjonctives cutanées bénignes. Encycl Méd Chir (Elsevier, Paris), Dermatologie, 98- 610-A-10, 1999, 22 p.
  9. Utermark T, Kaempchen K, Antoniadis G, Hanemann CO. Reduced Apoptosis Rates in Human Schwannomas. Brain Pathol 2005;15:17-22.
  10. Manganoni AM, Farisoglio C, Lonati A, Zorzi F, Tucci G, Pinton PG. Cutaneous epithelioid malignant schwannoma: review of the literature and case report. J Plast Reconstr Aesthet Surg 2009; 62:e318-21.