Effectiveness of acupuncture in treating schizophrenia: a clinical randomised trial about 31 patients

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Saoussen Bouhlel
Safouene El-Hechmi
Latifa Ghanmi
Mabrouk Ghaouar
Chokri Besbes
Mehrez Khaled
Wahid Melki
Zouhaier El-Hechmi

Abstract

Background: Acupuncture is one of the most popular types of complementary/alternative medicine in the world. It is sometimes used as a treatment for schizophrenia mainly in China.
Aim: To assess the contribution of acupuncture in the treatment of patients treated for schizophrenia in Tunisian population.
Methods: Our study is a clinical randomized trial about 31 hospitalized patients with schizophrenia or schizo-affectif disorder (DSM IV). They were evaluated by the Positive and Negative Syndrome Scale (PANSS), the Scale for the Assessment of Negative Symptoms (SANS) and the Scale for the Assessment of Positive
Symptoms (SAPS) the first and 23nd day of the study. Manual acupuncture was used for 10 sessions at the rate of three sessions per week. All patients were under drug therapy. Among them, 15 were treated by acupuncture and 16 by sham acupuncture.
Results: Scores of the PANSS, SAPS and SANS were similar in the two groups at the end of the study.
Conclusion: Our study did not provide any evidence for the effectiveness of acupuncture in treating schizophrenic symptoms.

Keywords:

Acupuncture - schizophrenia - antipsychotic -Tunisia.

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References

  1. Deniker P, Lemperiere T, Guyotat J. Précis de psychiatrie clinique de l'adulte. Paris: Masson, 1990.
  2. Arana GW. An overview of side effects caused by typical antipsychotics. J Clin Psychiatry 2000; 61: 5-11.
  3. Naber D. Long-term phase of schizophrenia: impact of atypical agents. Int Clin Psychopharmacol 2000; 15 : 11-4.
  4. Kane J, Honigfeld G, Singer J et al. Clozapine for the treatmentresistant schizophrenic. A double blind comparison with chlorpromazine. Arch Gen Psychiatry 1988; 45: 789-96.
  5. Ernst E, A White. Prospective studies of the safety of acupuncture: a systematic review. Am J Med. 2001; 110: 481-5.
  6. Mac Person H, Thomas K, Walters S, Fitter M. The York acupuncture safety study: prospective survey of 34000 treatments by traditional acupuncturists. BMJ 2001; 323 : 486-7.
  7. Kaptchuk TJ. Acupuncture: Theory, Efficacy, and Practice. American College of Physicians-American Society of Internal Medicine 2002; 136 : 374-83.
  8. Xu X. The English-Chinese Encyclopedia of Practical Traditional Chinese Medicine. Beijing : Higher Education Press 1991.
  9. Zhu Ming. The medical Classics of the yellow Emperor. Beijing: Foreign language Press 2001.
  10. Beecroft N, Rampes H. Review of acupuncture for schizophrenia. Acupunct Med 1997; 15:91-4.
  11. Rathbone J, Xia J. Acupuncture for schizophrenia. Cochrane Review. In: The Cochrane Library, Issue 2. Chichester, UK: John Wiley & Sons, Ltd. 2006.
  12. Lee MS, Shin BC, Ronan P, Ernst E. Acupuncture for schizophrenia: a systematic review and meta-analysis. Int J Clin Pract 2009; 63:1622-33.
  13. American Psychiatric association. DSM IV. Diagnostic and Statistical Manual of mental disorders, 4th edition. Washington, Dc: American Psychiatric press,1994.
  14. Kay SR, Fiszbein A, Opler LA. The positive and negative syndrome scale (PANSS) for schizophrenia. Schizophr Bull 1987; 13 : 261-76.
  15. Boyer P, Lecrubier Y. Fiche descriptive et traduction française de la SAPS. Psychiatrie et psychobiologie 1987 ; 6 :425-38.
  16. Boyer P, Lecrubier Y. Fiche descriptive et traduction française de la SANS. Psychiatrie et psychobiologie 1987 ; 2 :414-23.
  17. Zhang Y, Shao H, Zhao X. The clinical efficacy with intelligent electro-acupuncture of treating schizophrenia with depressive symptoms. Chin J Behavior Medl Sci 2001; 10 : 44-5.
  18. Gang Z, Shu bai J, Liang Dong Z. Comparative clinical study on the treatment of schizophrenia with electro-acupuncture and reduced doses of antipsychotic drugs. Am J Acupunct. 1997; 25 : 25-31.
  19. Vickers A, Goyal N, Harland R, Rees R. Do certain countries produce only positive results? A systematic review of controlled trials. Control Clin Trials 1998; 19:159-66.