Outcome at 2 years of very premature infants. A Tunisian series
##plugins.themes.academic_pro.article.main##
Abstract
Background: Neurodevelopmental outcome of very premature infant can be associated with a high rate of cerebral palsy.
Aim: To assess the impact of very preterm birth on neurological outcome at the age of two years.
Methods: Retrospective study of all cases of very premature infants born at less than 33 weeks of gestational age, during the years 2005 to 2007. Neurodevelopmental outcome is reported.
Results: During the study period, the very premature infant rate was 1.5 %. Acomplete information about neurological outcome at the ageof two years, was obtained in 60 cases.Eight infants (13.4%) showed major handicap (cerebral palsy) and four others infants developped neurosensoriel difficulties.
Conclusion: The incidence of neurosensoriel handicap in our population seems relatively high. A strong effort must be made for identification of risk factors of neurodevelopmental disability.
Keywords:
Infant premature; Mortality; morbidity, Follow-up##plugins.themes.academic_pro.article.details##
References
- Saigal S, Doyle L. An overview of mortality and sequelae of preterm birth from infancy to adulthood. Lancet 2008 ;371 :261-69.
- Larroque B, Ancel PY, Marret S, et al. Neurodevelopmental disabilities and use of special care needs of 5 year old children born before 33 week's gestation : the EPIPAGE study. Lancet 2008 ;371 :813-20.
- Allen MC. Neurodevelopmental outcomes of preterm infants. Curr Opin Neurol 2008 ;21 :123-28.
- Delobel Ayoub M, Kaminski M, Marret S et al. Behavioral outcome at 3 years of age in very preterm infants : the EPIPAGE study. Pediatrics 2006 ;117 :1996-2005.
- Moster D, Lie RT, MarkestadT. Long term medical and social consequences of preterm birth. N Engl J Med 2008; 359: 262-73.
- Bhutta AT, Cleves MA, Casey PH, Cradock MM, Anand KJS.Cognitive and behavioral outcomesof school aged children who were born preterm : a meta-analysis. JAMA 2002 ; 288 :728-37.
- Larroque B. Les troubles du développement des enfants grands prématurés mesurés à l'âge scolaire. J Gynecol Obstet Biol Reprod 2004; 33:475-86.
- Tin W, Fritz S, Wariyar U, Hey E. Outcome of very preterm birth: children reviewed with easeat 2 years differ from those followed up with difficulty. Arch Dis Child 1998 ;79 :83-87.
- Mc Carton CM, Brooks Gunn J, Wallace IF et al. Results at age 8 years of early intervention for low birth weightpremature infants. JAMA 1997; 277:126-32.
- Ben Hamida Nouaili E, Chaouachi S, Ben Said A, Marrakchi Z. Déterminants de la mortalité néonatale dans une population tunisienne. Tunis. Med 2010; 88: 42-45.