Allergic bronchopulmonary aspergillosis. A review of 3 cases.

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Published May 9, 2011
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Vol. 89 No. 5 (2011): Issue May 2011

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Leila Fekih
Leila Boussoffara
Hajer Ben Abdelghaffar
Soraya Fenniche
Ines Akrout
Hela Hassene
Dalenda Belhabib
Service de pneumologie Ibn Nafiss. Hôpital Abderrhmane MAMI de L'ARIANA
Mohamed Lamine Megdiche

Abstract

Background: Allergic bronchopulmonary aspergillosis (ABPA) is a rare affection, initially described in 1952. Its pathophysiology incriminate several mecanisms in relation with the organism of the patient and the bronchial colonisation by the fongic agent.
Aim: To report three cases of ABPA.
Cases report: Three patients had been treated for ABPA in Ibn Nafiss department in Abderrahmen Mami hospital in Ariana. ABPA had been discovered in the three cases by a corticodependant asthma, refractory for different therapeutics. Positif diagnosis reposed in the 3 patients at 6 major and one minor criterion. Traitment was essentially based in corticotherapy.
Conclusion: Positif diagnosis of ABPA is actually well established, however, its traitement, although based on corticotherapy, remind not clearly codified. Association of antifongic treatment may improve the prognosis.

Keywords:

Aspergillus, aspergillosis, asthma, treatment, corticotherapy

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