Adult’s cryptorchidism: clinical and therapeutic aspects About 100 cases
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Abstract
Background: Cryptorchidism is a pathological condition defined as the failure of the testis descending into the scrotum. It is a rare condition in adults.
Aim: To study clinical and therapeutic aspects of cryptorchidism in adults.
Methods: A retrospective study of a series of 100 adult patients (mean age: 25.1 years; 19-50 years) with cryptorchid testis admitted in an urology department in Tunis.
Results: The main reasons for consultation were the finding of an empty purse, inguinal pain and primary sterility. The testicle was palpable in 84 cases. The treatment consisted of an orchidopexy in most cases and in 14 cases orchydectomy.
Conclusion: Finding of cryptorchidism in adult is a real diagnostic failure. Surgical treatment is indicated to facilitate surveillance.
Keywords:
Testis, Cryptorchidism, Infertility, Cancer, Ultrasound, Orchidopexy, Orchidectomy##plugins.themes.academic_pro.article.details##
References
- Vinardi S, Magro P, Manenti M, et al. Testicular function in men treated in childhood for undescended testes. J Pediatr Surg. 2001; 36: 385-8.
- Farrer JH, Walker AH, Rajfer J. Management of the postpubertal cryptorchid testis: a statistical review. J Urol. 1985; 134: 1071-6.
- Grapin C, Geraud M, Audry G. Mécanisme de la non descente testiculaire. Chir Pediatr. 1989; 30: 134-7.
- Ben Jeddou F, Ghozzi S, Rais NB. La cryptorchidie de l'adulte: a propos de 81 cas. Tunis Med. 2005; 83: 742-5.
- Malone PS, Guiney EJ. A comparison between ultrasonography and laparoscopy in localising the impalpable undescended testis. Br J Urol. 1985; 57: 185-6.
- Nguyen HT, Coakley F, Hricak H. Cryptorchidism: strategies in detection. Eur Radiol. 1999; 9: 336-43.
- Bugel H, Pfister C, Liard-Zmuda A, Bachy B, Mitrofanoff P. Intérêt de l'exploration et du traitement par coelioscopie des testicules impalpables: à propos d'une série de 48 cas. Prog Urol. 1998; 8: 78-82.
- Mcheik JN, Levard G. Traitement laparoscopique des testicules impalpables. Résultats. Prog Urol. 2002; 12: 294-7.
- Debre B. Les tumeurs sur testicule cryptorchide. Ann Urol. 1984; 18: 253-5.
- Atilla MK, Sargin H, Yilmaz Y, Odabas O, Keskin A, Aydin S. Undescended testes in adults: clinical significance of resistive index values of the testicular artery measured by Doppler ultrasound as a predictor of testicular histology. J Urol. 1997; 158: 841-3.
- Frey P, Bianchi A. Microvascular orchiopexy. Eur J Pediatr. 1987;146 Suppl 2:S51-2.
- Dada R, Gupta NP, Kucheria K. Case report. Cryptorchidism and AZF microdeletion. Asian J Androl. 2002; 4: 148.
- Mieusset R, Bujan LE, Massat G, Mansat A, Pontonnier F. Inconstant ascending testis as a potential risk factor for spermatogenesis in infertile men with no history of cryptorchism. Hum Reprod. 1997; 12: 974-9.
- Ferlin A, Bettella A, Tessari A, Salata E, Dallapiccola B, Foresta C. Analysis of the DAZ gene family in cryptorchidism and idiopathic male infertility. Fertil Steril. 2004; 81: 1013-8.
- Hadziselimovic F. Cryptorchidism, its impact on male fertility. Eur Urol. 2002; 41: 121-3.
- Yavetz H, Harash B, Paz G, et al. Cryptorchidism: incidence and sperm quality in infertile men. Andrologia. 1992; 24: 293-7.
- Caroppo E, Niederberger C, Elhanbly S, Schoor R, Ross L, D'Amato G. Effect of cryptorchidism and retractile testes on male factor infertility: a multicenter, retrospective, chart review. Fertil Steril. 2005; 83: 1581-4.
- Toppari J, Kaleva M. Maldescendus testis. Horm Res. 1999; 51: 261-9.
- Arvis G, Nicourt Y. Cryptorchidie et fertilité. Ann Urol (Paris). 1984; 18: 246-52.
- Belas M. Stérilité et cryptorchidie. Chir Pediatr. 1989; 30: 148-50.
- Holm M, Hoei-Hansen CE, Rajpert-De Meyts E, Skakkebaek NE. Increased risk of carcinoma in situ in patients with testicular germ cell cancer with ultrasonic microlithiasis in the contralateral testicle. J Urol. 2003; 170: 1163-7.
- Carmona Campos E, Regueiro Lopez JC, Prieto Castro R, Leva Vahejo M, Moreno Arcas P, Requena Tapia MJ. Cryptorchidism and testicular cancer. Actas Urol Esp. 2000; 24: 49-51.
- Mottet N. Facteurs de risque du cancer du testicule et mécanisme de la carcinogénèse. Prog Urol. 2003; 13: 1244-5.
- Swerdlowa J, De Stabola BL, Swanwick MA, Mangtani P, Maconochie NE. Risk factors for testicular cancer: a case control study in twins. Br J Cancer. 1999; 80: 1098-2.
- Swerdlow AJ, Higgins CD, Pike MC. Risk of testicular cancer in cohort of boys with cryptorchidism. BMJ. 1997; 314: 1507-11.
- Toledano MB, Jarup L, Best N, Wakefield J, Elliott P. Spatial variation and temporal trends of testicular cancer in Great Britain. Br J Cancer. 2001; 84: 1482-7.
- Herrington LJ, Zhao W, Husson G. Management of cryptorchism and risk of testicular cancer. Am J Epidemiol. 2003; 157: 602-5.