Acute peritonitis complicating Crohn’s disease: Epidemiologic and physiopathological characteristics.

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Published Feb 7, 2011
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Vol. 89 No. 2 (2011): Issue Feb 2011

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Heykal Bedioui
Amine Daghfous
Oussama Baraket
Sofiene Chouaieb
Lamia Kallel
Sofiene Ayadi
Rabii Noomen
Faouzi Chebbi
Department of Surgery
Rachid Ksantini
Mohamed Jouini
Montacer Kacem
Zoubeir Ben Safta

Abstract

Background: An uncommon event in the natural course of Crohn’s disease is the spontaneous perforation. It’s the most serious intestinal complication.
Aim: To report the incidence of this complication and to discuss the mechanism of the perforation.
Observations: We report, retrospectively, 4 cases (3 men and one woman; median age: 30 years) of peritonitis complicating Crohn’s disease and study their clinical characteristics intra operatively findings and course evolution. Steroid therapy was administrated to all patients before the perforation. The perforation sites are on the
ileum in three cases and on the jejunum in one case. The treatment consists in a resection of the perforated intestine with stoma in all cases.
Conclusion: Perforation in Crohn’s disease is a rare event. The exact mechanism of the perforation is still unknown and many hypotheses are presented.

Keywords:

Crohn's disease, peritonitis, diagnosis, epidemiology, physiopathology, treatment

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