Inflammatory myofibroblastic tumor of the larynx: A case report

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Published Dec 2, 2010
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Vol. 88 No. 12 (2010): Issue Dec 2010

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Aida Goucha Chabbi
Nadra el Aouni Ben Mena
Wafa Rekik
Boutheina Debbabi
Slim Touati
Ahmed El may
Amor Gamoudi

Abstract

Background : Inflammatory myofibroblatic tumor is a recently caracterized solid mesenchymal tumor. They are frequently localised in the lung. However, the head and neck forms are uncommon.
Aim: To report a new case of inflammatory myofibroblastic tumor of the larynx.
Case report: This 47-year old man presented with dysphonia without dyspnea. Laryngoscopy showed a tumor of anterior vocal cord. CT scan of larynx confirmed diagnosis. The patient had a cordectomy. Histology concluded to the diagnosis of inflammatory myofibroblastic tumor. No relapses have been noted after 4 months.
Conclusion: Only a few cases of laryngeal inflammatory myofibroblastic tumor have been reported in the literature. Clinical presentation depends of tumor location. Radiological images are not specific and diagnosis is based on histology. The expected course is essentially marked by the risk of local recurrences. Surgical excision seems to be the treatment of choice.

Keywords:

Inflammatory myofibroblatic tumor, inflammatory pseudotumor, larynx

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References

  1. Sirvent N, Coindre JM. Inflammatory myofibroblastic tumors. Ann Pathol, 2002; 22: 453-60.
  2. Weiss SW. Histological typing of soft tumors. Berlin: springer- Verlag; 1994.
  3. Wening BM, Devaney K, Bisceglia M. Inflammatory myofibroblastic tumor of the larynx. Cancer, 1995; 76: 2217-29.
  4. Shek AW, Wu PC, Samman N. Inflammatory pseudotumor of the smooth and maxilla. J Clin Pathol, 1996; 49: 164-7.
  5. Treissman SP, Gillis DA, Lee CL, Giacomantonio M, Resch L. Omental-mesenteric inflammatory pseudotumor. Cytogenetic demonstration of genetic changes and monoclonality in one tumor. Cancer, 1994; 73: 1433-7.
  6. Coffin CM, Fletcher JA. Inflammatory myofibroblastic tumors. In: Fletcher CDM, Unni KK, Mertens F, editors. World Health Organisation Classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARC Press: 2002. p 91-3.
  7. 7-Rodriguez M, Taylor RJ, Sun CC, Wolf JS. Inflammatory myofibroblastic tumor of the larynx in a 2-year-old male. ORL J Otorhinolaryngol Relat Spec 2005; 67: 101-5.
  8. Donner LR, Trompler RA, White RR. Progression of inflammatory myofibroblastic tumor (inflammatory pseudotumor) of soft tissue into sarcoma after several recurrences. Human Pathol, 1996; 27: 1095-8.
  9. Dehner LP. The enigmatic inflammatory pseudotumours: the current state of our understanding or misunderstanding. J Pathol, 2000; 192: 277-9.
  10. Chaturvedi P, Rodriguez G, Sanghvi VD. Pseudo-malignant laryngeal nodule. Histopathology 1999; 34: 272-3.
  11. Janik JS, Janik JP, Lovell MA, Hendrickson RJ, Densard DD, Greffe BS. Recurrent inflammatory pseudotumours in children. J Pediatr Surg, 2003; 38: 1491-5.