Pseudo Tumoral Gastric Amyloidosis: About A Rare Case Report

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Published Sep 1, 2010
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Vol. 88 No. 9 (2010): Issue Sep 2010

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Haifa Nfoussi
Ines Chelly
Khadija Bellil
Nidhameddine Kchir
Slim Haouet
Moncef Zitouna

Abstract

Background: Amyloidosis is an abnormal extracellular deposition of insoluble proteins, which is associated with an involvement of the gastrointestinal tract in 50 to 70% of cases. In primary amyloïdosis (light chain amyloïdosis), localized gastric involvement is a rare finding which can mimick malignancy.
Aim: to elucidate the clinical, histological and therapeutic features of pseudo tumoral gastric amyloidosis via a rare report along with a review of related literatures.
Observation: We report the case of a 56-year-old man, admitted with upper digestive outlet obstruction. Linitis plastica with lymph node involvement was suspected by gastroscopy, barium meal and endoscopic ultrasonography but was not confirmed by gastric biopsies. The patient was treated with total gastrectomy with lymph
node dissection.
Results: Pathological examination demonstrated gastric and lymph nodes amyloidosis and no malignant tumor was found.
Conclusion: we propose that amyloidosis should be considered in the differential diagnosis of gastric tumors.

Keywords:

Amyloidosis, stomach, pathology

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