Upper urinary tract infections in adults: about 261 episodes

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Rim Abdelmalek
Badreddine Kilani
Fakher Kanoun
Lamia Ammari
hanène Tiouiri Benaissa
Ahmed Goubontini
Faycal Zouiten
Taoufik Ben Chaabane

Abstract

Background : Upper urinary tract infections are frequent. Escherichia coli is the main pathogen identified from community acquired infections.
Aim : We aim to study epidemiologic, clinical and bacterial features of this infection.
Methods: We identified 261 episodes that occurred in 241 patients. They were 213 females and 48 males aged of 48,75 years. Enterobacteriaceae were the main pathogens isolated in 93,5%: E. coli in 73,3% and Klebsiella pneumoniae in 15,3%. E. coli sensitivity was of 30% for amoxicillin, 98% for cefotaxim, 96% for gentamicin, 90% for ciprofloxacine and 56% for co-trimoxazole. Anterior antibiotic use was associated with low E. coli sensitivity mainly with fluoroquinolones (96 vs 77%) and co-trimoxazole (62 vs 43%). This enhances the role of antibiotic pressure on the resistance emergence.
Conclusion: the reasonable use of antibiotics is necessary to limit resistance extent.

Keywords:

Upper urinary tract infection, Escherichia coli, enterobacteriaceae, bacterial resistance

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