The Prophylaxis Of The Thromboembolic Disease In The Head Trauma

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Published Aug 3, 2010
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Vol. 88 No. 8 (2010): Issue Aug 2010

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Nabil Frikha
Service d'Anesthésie-Réanimation à CHU Mongi Slim - La Marsa - Tunisie
Sonia Ouerghi
Mohamed Ali Mnif
Mhamed Sami Mebazaa
Service d'Anesthésie-Réanimation à CHU Mongi Slim - La Marsa - Tunisie
Mohamed Salah Ben Ammar
Service d'Anesthésie-Réanimation à CHU Mongi Slim - La Marsa - Tunisie

Abstract

Background : The prophylaxis of the thromboembolic disease in the severe head trauma remains a controversy.
Aim: In this study, we are interested to the determination of under groups of patients for whom the advantages of the prophylaxis of the thromboembolic disease (TED) are higher than its disadvantages.
Methods: We proceeded to a retrospective study based on patient medical records ranging from March 2003 until March 2004, enrolling 56 consecutive patients. The data collected related to the age, the gender, past medical history, the type of trauma, results of the initial CT scan, the treatment, appearance or not of the
thromboembolic disease and its prophylaxis therapy.
Results: The average age was of 36±19 years. 76.8% did not have significant past medical history. All the patients profited from an elastic compression stocking. The LMWH were used among 15 patients victim of severe head trauma associated with other injuries and 72 hours after stabilization of hemorrhagic attacks. A
thromboembolic disease diagnosis was based clinical or biological assumptions. Among 56 patients, 4 of them showed a TED with an incidence of 7.1 including 3 DVT and one case of pulmonary embolism. The 4 patients sustain severe multiple trauma; 3 of them received an early anti-coagulation therapy. In the group of patients with TED, the OMEGA scores and IGS are high; all of them are multiple traumatized patients with shock requiring a blood transfusion in 75 of the cases. Only the blood transfusion is correlated at the risk of TED, statistically established.
Conclusion: The risk to develop a thromboembolic complication in the traumatic patients with head injury is high particularly in case of associated muscleskeletal injuries. Elastic compression technique is not always effective but considered as an interesting alternative to the pharmacological prevention of thrombosis. The use of the anticoagulants therapy must be careful. It is contra-indicated in case of cerebral haemorrhage in progress and must be considered upon individual case of each patient.

Keywords:

Brain injury, thromboembolic disease

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