Late Stent Thrombosis In a Young Patient who had Ulcerative Colitis .

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Published May 31, 2010
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Vol. 88 No. 6 (2010): Issue Jun 2010

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Salem Abdessalem
Nizar Annabi
Sami Mourali
Rachid Mechemeche

Abstract

Background : Arterial and venous thrombosis are well recognized systemic complications of inflammatory bowel disease predominantly in patients with crohn’s colitis and in those with ulcerative colitis (UC).
Aim : report a new case
Case : We describe the case of a 35 years old man presenting previously an anterior infarct with a tighten stenosis in the middle part of the left anterior descending artery (LAD). The stenosis was treated percutaneously with a bare stent deployment. During an acute exacerbation of UC, the patient developed an acute coronary
syndrome with ST elevation secondary to a late stent thrombosis, needing a primary coronary angioplasty. Following course is
favorable.
Conclusion : Based on this case, we’ll discuss the relationship between UC and thrombosis, and therapeutic considerations inherent to thrombotic and bleeding risks.

Keywords:

Thrombosis, stent, ulcerative colitis, inflammation

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References

  1. Talbot RW, Heppel J, Dozois RR et al. Vascular complications of inflammatory bowel disease. Mayo Clin Proc. 1986 ;61 :140-5.
  2. Colombel JF, Desreumaux P, Klein O. Maladies inflammatoires chroniques de l'intestin. Hepato-Gastro 1994; 2:143-55
  3. Cortot A. Maladies inflammatoires chroniques de l'intestin. ATraitement médical. Hepato-Gastro 1994; 6 : 541-50
  4. Vissuzaine C, Danne O, Jouglin J, Soullard J, Mignon M. Les lésions histologiques du rectum restant après anastomose iléorectale pour rectocolite hémorragique. Gastroenterol Clin Biol 1979 ; 3 : 631-6
  5. Efremidis M, Prappa E, Kardaras F. Acute myocardial infarction in a young patient during an exacerbation of ulcerative colitis. Int J Cardiol 1999; 70:211-2.
  6. Mutlu B, Ermeydan M.H , Feruze E et al. Acute myocardial infarction in a young woman with severe ulcerative colitis. International Journal of Cardiology 2002; 83:183 -5
  7. Batty V, Blain H, Saadi L et al. Fatal myocardial infarction in an elderly woman with severe ulcerative colitis : what is the role of steroids? Am J Gastroenterol 1998; 93:2000-1.
  8. Thompson NP, Wakefield AJ, Pounder RE. Inherited disorders of coagulation appear to protect against inflammatory bowel disease. Gastroenterology 1995; 108:1011-5
  9. Gaffney PR, Doyle CT, Gaffney A et al. Paradoxical response to heparin in 10 patients with ulcerative colitis. Am J Gastroenterol 1996; 91:1221-5.