Calciphilaxis in chronic renal failure : 3 cases

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Published Apr 3, 2010
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Vol. 88 No. 4 (2010): Issue Apr 2010

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Hayet Kaaroud
Soumaya Béji
Ines Souissi
Fethi Ben Hamida
Karim Zouaghi
Fatma Ben Moussa
Fethi El Younsi
Ezzedine Abderrahim
Taieb Ben Abdallah
Hedi Ben Maiz
Adel Khedher

Abstract

Background: Calciphylaxis is a small vessel disease responsible for vascular calcification and skin necrosis. It occurs in association with chronic renal failure and has a poor prognosis.
But : Report new cases. We report 3 cases of calciphylaxis occurred in patients with chronic renal failure secondary to interstitial nephritis in 1 case, diabetic nephropathy in 1 case and thrombotic microangiopathy in 1 case.
Cases: They were 2 females an 1 man aged of 44,3 years meanly. Hyperphosphoremia and hyperparathyroidism were the essential risk factors. All patients died by sepsis. This course was precipitating by corticotherapy in 2 cases.
Conclusion: Early recognition and treatment of risk factors is mandatory to reduce mortality in uremic patients with calciphylaxis

Keywords:

Calciphylaxis, Chronic renal failure, Haemodialysis, Mortality

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