Acute disseminated encephalomyelitis associated with Mycoplasma pneumoniae infection in children 2 case reports
##plugins.themes.academic_pro.article.main##
Abstract
Background : Extrapulmonary complications of Mycoplasma pneumoniae infection are rare and dominated by nervous system disorders. Two patients suffering from acute disseminated encephalomyelitis associated with M. Pneumoniae infection are reported.
Aim : the 2 cases, M. Pneumoniae infection was documented by the positivity of serology, polymerase chain reaction and culture in the respiratory tract. Patient 1 recovered after prolonged mechanical ventilation in the paediatric intensive care unit. He was fully conscious 1 month after admission and able to walk with help 2.5
months after the onset of the disease. The 2nd patient died after 9 days of hospitalisation in the intensive care unit. The death was caused by neurovegetative disorders.
Keywords:
Mycoplasma Pneumoniae, Acute disseminated encephalomyelitis, Post infectious##plugins.themes.academic_pro.article.details##
References
- Tsiodras S, Kelesidis T, Kelesidis I, Voumbourakis k, Giamarellou H. Mycoplasma pneumoniae-associated myelitis: a comprehensive review. Eur J Neurol 2006; 13(2):112-24.
- Yifl U, Kurul Sh, Cakmakçi H, Dirik E. Mycoplasma pneumoniae : nervous system complications in childhood and review of the literature. Eur J Pediatr 2008; 167(9):973-8.
- Stamm B, Moschopulos M, Hungerbuehler H, Guarner J, Genrich Gl, Zaki SR. Neuroinvasion by Mycoplasma pneumoniae in acute disseminated encephalomyelitis. Emerg Infect Dis 2008; 14(4): 641-3.
- Pfausler B, Engelhardt K, Kampfl A, Spiss H, Taferner E, Schmutzhard E. Post-infectious central and peripheral nervous system diseases complicating Mycoplasma pneumoniae infection. Report of three cases and review of the literature. Eur J Neurol 2002; 9(1): 93-6.
- Sotgiu S, Pugliatti M, Rosati G, Deiana Ga, Sechi GP. Neurological disorders associated with Mycoplasma pneumoniae infection. Eur J Neurol 2003; 10(2):165-8
- Christie Lj, Honarmand S, Talkington DF, et al. Pediatric encephalitis: what is the role of Mycoplasma pneumoniae? Pediatrics 2007; 120(2): 305-13.
- Krupp Lb, Banwell B, Tenembaum S, International Pediatric Ms Study Group. Consensus definitions proposed for pediatric multiple sclerosis and related disorders. Neurology 2007; 68 (16 Suppl 2): S7-12.
- Bitnun A, Ford-Jones E, Petric M, et al. Acute childhood encephalitis and Mycoplasma pneumoniae. Clin Inf Dis. 2001; 32:1674-84.
- Krishnan C, Kaplin A, Deshpande D, Pardo C, Kerr Da. Transverse myelitis: pathogenesis, diagnosis and treatment. Front Biosci 2004; 9:1483-99.
- Nishimura M, Saida T, Kuroki S, et al. Post-infectious encephalitis with anti-galactocerebroside antibody subsequent to Mycoplasma Pneumoniae infection. J Neurol Sci 1996; 140:91-95.