ODONTOGENIC DESCENDING NECROTIZING MEDIASTINITIS.

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Slim Jarboui
Hichem Jerraya
Amir Moussi
Mounir Ben Moussa
Mounir Marrakchi
Nadia Kaffel
Karim Haouet
Mohamed Ferjaoui
Abdeljelil Zaouche

Abstract

Backgrpound : Descending necrotizing mediastinitis (DNM) following an oropharyngeal infection is a rare disease with a rapid course and a mortality rate of up to 40%. The aim of this study, is to outline the diagnosis and the appropriate treatment of DNM.
Materiels and Methods: A retrospective study (1986-2007) of patients with DNM was made. Only patients with cervical cellulitis associated with DNM were included.
Results: Eight men and two women with an average age of 43 years were treated. Five had diabets. The average for diagnosis and treatment was eight days. In eight cases, we found a dental origin and in two cases a pharyngeal origin. The diagnosis of DNM was made thanks to cervico thoracic CT scan in six cases. In the others patients, they had at presentation clinical and radiological evidence of mediastinal diffusion. All patients were treated by broad spectrum
antibiotherapy. All had cervical drainage. Mediastinal drainage was made by cervical approach in 2 two cases and via a right thoracotomy in eight cases. Eight patients died.
Discussion: Odontogenic DNM is a rare disease with rapid course. Clinical diagnosis is difficult and early recognition with a low thresold for CT scanning is essential. CT is also useful for the treatment and in the post operative assessment. All affected tissue plane must be debrided. Surgical management and mediastinal drainage remain controversial about the indication of thoracotomy.

Keywords:

Cellulitis, mediastinitis, odontogenic infection, cervicotomy, thoracotomy

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References

  1. Estera AS, Lanay MJ, Grisham JM et al. Descending necrotizing mediastinitis. Surg Gynecol Obstet 1983 ; 157 : 545-52.
  2. Verdalle PB, Roguet E, Raynal M, Briche T, Rouquette I, Brinquin L, Jancovici R, Poncet JL. Les cellulites cervico mediastinales nécrosantes. A propos de 3 cas. Ann Otolaryngol Chir Cervicofac 1997 ; 114 : 302-309.
  3. Corsten MJ , Shamji F.M , Odell PF , Frederico JA, Laframboise GG, Reid KR, Valliers E, Matzinger F; Optimal treatment of descending necrotising mediastinitis. Thorax 1997 ; 52 : 702-708.
  4. Marty -Ane CH, Alauzen M, Alric P, Serres - Cousine O, Mary H. Descending necrotizing mediastinitis. Advantage of médiastinal drainage with thoracotomy. J Thorac Cardiovasc Surg 1994; 107:55-61.
  5. Trabelsi O, Khiareddine T, Abdesselem MM, Zaouche A, Ennebli E. Les mediastinites aiguës d'origine dentaire : A propos de 4 observations. Tunis Chir 1994 ; 3 : 162-166.
  6. Takao M, Ido M, Hamaguchi K, Chkusa H, Namikawa S, Kusagawa M. Descending necrotizing mediastinitis secondary to a retropharyngeal abscess. Eur Respir J 1994; 7: 1716-1718.
  7. Honguero Martinez AF, Arnau Obrer A, Centeno Fernandez A, Perramon Saumench R, Estors M, Armengod C. Descending necrotizing mediastinitis : Treatment by transcervical thoracic drainage. Arch Broncopneumol 2005; 41: 293-4.
  8. Casanova J, Bastos P, Barreiros F, Rodrigues Gomes M. Descending necrotizing mediastinitis _ succesful treatment using a radical approach. European Journal of Cardio-thoracic Surgery 1997; 12: 494-496.
  9. Bulut M, Balci V, Akkose S, A rmagan E. Fatal descending necrotizing mediastinitis. Emerg Med J 2004 ; 21 : 122-123.
  10. Haar R. P.S, Cranstom C, Warwick-Brown N. Descending necrotizing mediastinitis : report of a case following steroid neck injection. The Journal of Laryngology and Otology. 2002; 116: 862-864.
  11. Kiernan PD, Hernadez A, Byerne W.D, Bloom R, Dicicco B, Hertrick V, Graling P, Vaughan B. Descending cervical mediastinitis. Ann Thorac Surg 1998; 65: 1483-8.
  12. Hirai S, Hamanaka Y, Mitui N, Isaka M, Mizukami T. Surgical treatment of virulent descending necrotizing mediastinitis. Ann Thorac Cardiovasc Surg 2004; 10: 34-8.
  13. Brunelli A, Sabbatini A, Catalini G, Fianchini A, Descending necrotizing médiastinitis. Arch Otolaryngol Head Neck Surg 1996 ; 122 : 1326-29.
  14. Weathley MJ, Strling MC, Kirsh MM, Gago O, Orringer MB. Descending necrotizing mediastinitis : Transcervical drainage is not enough. Ann Thorac Surg 1990; 49: 780-4.
  15. Mihos P, Potaris K, Gakidis I, Papadakis D, Rallis G. Management of descending necrotizing médiastinitis. J Oral Maxillofac Surg 2004; 62: 966-72.
  16. Iwata T, Sekine Y, Shibuya K, Yasufuku K, Iyoda A, Iizasa T, Saito Y, Fujisawa T. Early open thoracotomy and mediastinopleural irrigation for severe descending necrotizing mediastinitis. Eur J Cardiothorac Surg 2005; 28: 384-8.
  17. Kruyt P.M, Van Lanschot J.B, Broonstra A, Fockens P, Reeders J. W. A.J. Descending necrotizing mediastinitis causing pleuroesophageal fistula: Succesful treatment by combined transcervical and pleural drainage. Chest;1996: 1404-1407.
  18. Kato H, Ohkubo N, Akazawa K, Iseki H, Haruna M. Spontaneous closure of a large tracheal fistula due to descending necrotizing mediastinitis. Ann Thorac Surg 2000; 69: 1249-51.
  19. Roberts J.R, Smythe R, Weber R. W, Lanuti M, Rosengard B.R, Kaiser L. R. Thoracoscopic management of descending necrotizing madiastinitis. Chest 1997; 112: 850-54.
  20. Isowa N, Yamada T, Kijima T, Hasegawa K, Chihara K. Succesful thoracoscopic debridement of descending necrotizing médiastinitis. Ann Thorac Surg 2004; 77: 1834-7.
  21. Shupak A, Letter to the Editor. Ann Otol Rhinol Laryngol 1990; 100: 432.