ADAPTATION OF A SOFT-SIGNS SCALE TO CHILDREN WITH AUTISM SPECTRUM DISORDERS

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Published Dec 4, 2009
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Vol. 87 No. 10 (2009): Issue Oct 2009

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S Halayem
A Bouden
I Amado
M Odile
M.Odile Krebs
K Tabbane
M Halayem

Abstract

Background: Neurological soft signs (NSS) are endophenotypic markers of schizophrenia, and their high prevalence in pervasive developmental disorders (PDD) support the existence of the spectrum of psychoses. These NSS were evaluated by standardized scales which were not adapted to children with PDD.
Aims: This study aimed to propose an adaptation for children of a scale of NSS already used in adults.
Methods: 21 children with PDD (11 with autistic disorder, 10 with PDD not otherwise specified) aged 6-12 years and 21 controls matched on age, sex, and cognitive level were included. Evaluating tools were NSS scale of Krebs et al. adapted after a pilot-study with the accordance of its author; the Progressive Matrices of Raven for intellectual level, and ADI-R to confirm diagnosis.
Results: Patients were significantly more impaired on total score (p=0,001), motor coordination (p=0,008), motor integration (p=0,000), and sensory integration (p=0,001). There were no difference between patients and controls on abnormal movements and quality of lateralization.
Conclusion: This adaptation of Krebs et al. scale seems to be a good tool for evaluating NSS in children, especially in those with PDD. A further validation study, including a larger sample is necessary.

Keywords:

Pervasive developmental disorders, neurological soft signs

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References

  1. LORD C; RUTTER M; LECOUTEURA. Autism diagnostic interview revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders1994; 24: 659-85.
  2. BARTHELEMY C ; ADRIEN JL ; LELORD G. Echelles dans l'autisme de l'enfant. Dans : Lelord G, Sauvage D. L'autisme de l'enfant. Paris: Masson, 1999: 99-113.
  3. AMERICAN PSYCHIATRIC ASSOCIATION. Diagnostic and Statistical Manual of Mental Disorders (4th Edition). Washington DC, USA: American Psychiatric Association, 1994.
  4. DEWEYD; CANTELLM; CRAWFORD SG. Motor and gestural performance in children with autism spectrum disorders, developmental coordination disorder, and/or attention deficit hyperactivity disorder. J Int Neuropsychol Soc. 2007; 13: 246-56.
  5. GHAZIUDDIN M; BUTLER E. Clumsiness in autism and Asperger syndrome: a further report. Journal of intellectual Disability Research 1998; 42: 43-8.
  6. HENDERSON SE; SUGDEN D. The movement assessment battery for children. London: The Psychological Corporation, 1992
  7. MANJIVIONAJ; PRIOR M. Comparison of Asperger syndrome and high-functioning autistic children on a test of motor impairment. Journal of autism and developmental disorders 1995; 25: 23-9
  8. MIYAHARAM; TSUJII M; HORI M; NAKANISHI K; KAGEYAMAH; SUGIYAMAT. Brief report: Motor in schizophrenia. incoordination in children with Asperger syndrome and learning disabilities. Journal of autism and developmental disorders 1997; 27: 595-603.
  9. HUBER J; HENDERSON SE. The severity and nature of motor impairment in Asperger's syndrome: a comparison with specific developmental disorder of motor function. Journal of Child Psychology and Psychiatry 2002; 50: 1304-8.
  10. Quantitative assessment of neuromotor functions in adolescents with high functioning autism and Asperger syndrome. Journal of Autism and Developmental Disorders 2007; 37: 948-59
  11. JANSIEWICZ EM; GOLDBERG MC; NEWSCHAFFER CJ; DENCKLAMB; LANDAR; MOSTOFSKYSH. Motor signs distinguish children with higfunctioning autism and Asperger4s syndrome from controls. Journal of autism and developmental disorders 2006; 36: 613-21.
  12. MANDELBAUM DE. Sensorimotor performance in school-age children with autism, developmental language disorder, or low IQ. Developmental Medicine & Child Neurology 2006; 48: 33-9
  13. KREBS MO ; GUT-FAYAND A; BOURDELMC ; et al. Validation and factorial structure of a standardized neurological examination assessing neurological soft signs in schizophrenia. Schizophrenia Research 2000; 45: 245-60.
  14. GOURION D ; GOLDBERGER C ; BOURDELMC ; et al. Neurological soft-signs and minor physical anomalies in schizophrenia: differential transmission within families. Schizophrenia Research 2003; 63: 181-7
  15. MECHRI A; SLAMAH; CHEBELS ; et al. Traitement neuroleptique et signes neurologiques mineurs chez les patients schizophrènes. Thérapie 2007; 62: 449-53
  16. RAVEN JC ; COURTJH ; RAVEN J. Progressives Matrices Couleur. Paris: ECPA, 2004.
  17. FAMBONNE E. Epidémiologie des troubles psychiatriques en pédopsychiatrie. EMC Psychiatrie; 2005: 169-94.
  18. RUTTER M; SCHOPLER E. Autism, a reappraisal of concepts and treatment. New York: Plenum Press, 1978: 207
  19. CHAKRABARTI S; FOMBONNE E. Pervasive Developmental Disorders in preschool children: confirmation of high prevalence. Am J Psychiatry 2005; 162: 1133-41
  20. HAUCK JA; DEWE D. Hand preference and motor functioning in children with autism. Journal of Autism and Developmental Disorders 2001; 31: 265-77.
  21. SATZ P; SOPER HV; ORSINI DL. Human hand preference: Three nondextral subtypes. Dans Molfese DC, Segalowitz SJ. Brain lateralization in children: Developmental implications. New York: Guilford Press, 1988: 281-7