ULCERATIVE COLITIS AND SCHIZOPHRENIA : FORTUITOUS ASSOCIATION OR ETIOPATHOGENIC LINK ?

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R. Ennaifer
R. Rafrafi
L. Mouelhi
F. Houissa
S. Bouzaidi
S. Trabelsi
Z. El Hechmi
T. Najjar

Abstract

Background: Ulcerative colitis is a chronic inflammatory bowel disease with multiple pathogenic factors. Psychiatric disorder have frequently been associated to ulcerative colitis, the most frequent being depression and anxiety, whereas schizophrenia is unusual.
Aim : Report a new case of ulcerative colitis associated topsychiatric disorder.
Case-report: We report the case of a 42-year-old woman with ulcerative colitis associated with schizophrenia. Although the two diagnoses were concomitant, on questioning, she revealed that digestive symptoms began before psychiatric disorders.
Conclusion: Few cases of schizophrenia associated with ulcerative colitis have been reported in the literature. We discuss epidemiological, etiopathogenic and therapeutic links between the two diseases.

Keywords:

Schizophrenia, Ulcerative colitis, Comorbidity

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