DITRIBITION AND PREVALENCE OF DYSLIPIDEMIA IN TUNISIA: RESULTS OF TUNISIAN NATIONAL NUTRITION SURVEY

##plugins.themes.academic_pro.article.main##

Olfa Essais
Jabrane Jabrane
Radhia Bouguerra
Jalila El Atti
Chiheb Ben Rayana
Sadok Gaïgi
Claude Ben Slama
Béchir Zouari

Abstract

The aims of the study were to study the distribution of cholesterol and triglycerides and to assess the prevalence of dyslipemia in Tunisian adult population.
Methods : The Tunisian National Nutrition Survey (TNNS) was a cross sectional study performed on a total of 7860 adult subjects and was conducted on1996-1997. The TNNS included 3087 adults over 20 years old.
Results : The mean values of cholesterol (CT) were more elevated in urban than rural area (p<0,001), and in females than in males (p<0,007). The overall prevalence of hypercholesterolemia (CT > 6,2 mmol/l) was 8,4% and that of hypertriglyceridemia (TG > 1,70 mmol/l) was 21%. The prevalence of borderline high cholesterol (³5,2 - < 6,2 mmol/l) was 17% ; These prevalences were more elevated in urban than rural areas (p < 0,001) and increased with age in both genders (p < 0,001). The multiple adjusted odd ratio of the prevalence of hypercholesterolemia showed a positive correlation with female sex (OR 1.40 p < 0,01), high waist circumference (OR
2.51 in men and 3,04 in women p < 0001) and urban residency (OR 1.35 p = 0,03).
Conclusion: Our study showed the metabolic consequences of westernization style life in our country and should be the starter to preventive adequate policy.

Keywords:

hypercholesterolemia, hypertriglyceridemia, prevalence, central obesity, epidemiology

##plugins.themes.academic_pro.article.details##

References

  1. Hajem S. 2001. - Statistique Nationale (Les causes médicales de Décès),INSP 2002.
  2. Bouguerra R., Ben Salem L., Alberti H., Ben Rayana C., et all. - Prevalence of metabolic abnormalities in the tunisian adults: a population based study. Diabetes and Metabolism 2006; 32 : 215- 21.
  3. Bouguerra R., Alberti H., Ben Salem L., Ben rayana C. et all. - The global diabetes pandemic : the Tunisian experience. Eur J Clin Nutr 2007;61:160-5
  4. Lindström J., Louheranta A., Mannelin M., Rastas M. et all. - The Finnish Diabetes Prevention Study (DPS) : Lifestyle intervention and 3 year results on diet and physical activity. Diabetes care 2003; 26: 3230-6.
  5. Sempos CT., Cleeman JI., Carroll MD., Johnson CL., et al. - Prevalence of High Blood Cholesterol Among US Adults. JAMA 1993; 269: 3009-16.
  6. Ben Khelifa F, Ben dridi M, El Aïssi N, Papoz L, Eschwege E, Ben Ayed H.- Cholesterolemia in the Tunisian population. Tunis Med 1981;59: 424-31
  7. Executive Summary of the Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of Hight Blood Cholesterol in Adults (Adult Treatment Panel III). JAMA 2001; 285: 2486- 2491.
  8. Alberti KG., Zimmet P., Shaw J. IDF Epidemiology task Force consensus group. - The metabolic syndrome- a new worldwide definition. Lancet 2005; 366: 1059-62.
  9. Distributions of total Cholesterol, LDL Cholesterol, HDL Cholesterol, and triglycerides in the U.S. Adult Population, NHNES III Data (1988-1994) (Serum). Circulation 2002; 106: 3235-3240.
  10. Sekuri C., Eser E., Akpinar G., Cakir H., Sitti I., Gulomur O., Ozcan C. - Cardiovascular disease risk factors in postmenopausal women in West Anatolia. Jpn Heart J. 2004; 45: 119- 31
  11. Al-Lawati, JA Jawad and Pekka Jousilahti. Body mass index, waist circumference and waist-to-hip ratio cut-off points for categorisation of obesity among Omani Arabs. Public Health Nutr 2008;11: 102-8
  12. Azizi F., Rahmani M., Ghanbarian A., Emami H., Salehi P., Mirmiran P., Sarbazi N. - Serum lipid levels in an Iranian adults population: Tehran Lipid and Glucose Study. Eur J Epidemiol 2003; 18: 311-9.
  13. Chen Z., Peto R., Collins R., MacMahon S., Lu J., Li W. - Serum cholesterol concentration and coronary heart disease in population with low cholesterol concentrations. BMJ 1991;303:276-82
  14. Law MR., Wald NJ., Thompson SG. - By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease. BMJ 1994; 308: 367-372.
  15. Law MR., Wald NJ., Rudnicka AR. - Quantifying effect of statins on low density lipoprotein cholesterol, ischaemic heart disease, and stroke: systematic review and meta-analysis. BMJ 2003; 326:1423.
  16. Ortola J., Castineiras MJ., Funtes-Arderiux X. - Biological variation data appmied to the ratios used as risk markers of coronary heart disease. Clin. Chem 1992; 3B: 56-59.
  17. Carroll MD., Lacher DA., Sorlie PD., Cleeman JI., Gordon DJ., Wolz M., et al. - Trends in serum lipids and lipoproteins of adults, 1960 - 2002. JAMA 2005; 294: 1773-81.
  18. Rguibi M., Belhassen R. - Metabolic syndrome among Moroccan Sahraoui adult women. Am J Human Biol 2004; 16: 598-601
  19. Ben Romdhane H., Haouala H., Ben Hani A., Drissa H., et Coll. - La transition épidémiologique ses déterminants et son impact sur les systèmes de santé a travers l'analyse de la tendance des maladies cardio-vasculaires en Tunisie. Tunisie Médicale 2005; 83: 1-7
  20. Ruixing Y., Yuming C., Shanglin P., Fenqping H., et all. - Comparison of lipid levels, Hyperlipidemia. Prevalence and its risk Factors between Guangxi Hei Yi. Zhuang and Han Populations. Arch Med Res. 2006; 37: 787-93
  21. Mensah GA., Mokdad AH., Ford ES., Greenlund KJ., Croft JB. - State of disparities in cardiovascular health in the United States. Circulation 2005; 111: 1233-41.
  22. Siest G., Henny J., Schiele F.- Cholestérol total in : Références en Biologie Clinique. Paris : Elsevier 1990: 193-209
  23. Dalpino FB., Sodre FL., de Faria EC. - The use of a hospital laboratory cohort to estimate the prevalence of dyslipidemia in an adult Brazilian population. Clin Chim Acta 2006; 367: 189-91.
  24. Pong chaiyakull C., Pratipanawatr T. - Prevalence of dyslipidemia in rural thai adults. J. Med. Assoc Thai 2005; 88: 1092-7.
  25. Harzallah F., Alberti H., Ben Khalifa F. - The metabolic syndrome in an Arab population : a first look at the new International Diabetes Federation criteria. Diabet Med 2006; 23: 441- 4.
  26. Huxley R., Barzi F., Woodward M. - Excess risk of fatal coronary heart disease associated with diabetes in men and women: metaanalysis of 37 prospective cohort studies. BMJ 2006; 332: 73-8
  27. Trémollières FA., Pouilles JM., Cauneille C., Ribot C. - Coronary heart disease risk factors and menopause : a study in 1684 French women. Atherosclerosis 1999; 142: 415-23.