INTERNALMAMMARY LYMPH NODE INVASION IN BREAST CANCER : MYTH OR REALITY ?

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Mongi Maalej
Walid Gargouri
Lotfi Kochbati
Chiraz Nasr
Hatem Frikha
Dalenda Hentati
Noomène Elkadri
Tarek Kraiem
Ali Chebbi
Amor Saadi
Karima Mrad
Abdelfattah Zakhama
Monia Hechiche
Khaled Ben Romdhane

Abstract

The internal mammary nodes are often underestimated as breast cancer lymphatic pathway spread. It is yet the first site of lymphatic invasion in central or internal tumors and the second site in external tumors. The intra-thoracic situation of internal mammary nodes explains partly, the difficulty of its exploration. To evaluate the risk of internal mammary node invasion, some predictive factors are established (tumor size, internal or central tumor location, axillary node invasion and young age). Prognostic and therapeutic impact of invasion justifies its systematic research. Without exploring internal mammary nodes status, TNM classification remains incomplete. CT scanner, magnetic resonnance imaging, positron emission tomography scanner and sentinel node exploration technique are helpful to explore this region and to adapt its irradiation.

Keywords:

internal mammary node, Breast cancer, investigation

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