REVIEW OF 32 GASTRO-INTESTINAL STROMAL TUMOURS WITH CD117

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Vol. 87 No. 2 (2009): Issue Feb 2009

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Ahlem Lahmar-Boufaroua
service d'anatomie et cytologie pathologique. Hôpital Farhat Hached Sousse
Sana Ben Slama
Service d'Anatomie Pathologique
Saadia Bouraoui
Service d'Anatomie Pathologique
Lassaad Gharbi
Service de Chirurgie Générale Hôpital Mongi Slim La Marsa - Tunisie
Carole Goutallier
Service d'Anatomie Pathologique
Saber Manai
Service de Chirurgie Générale Hôpital Mongi Slim La Marsa - Tunisie
Walid Gharbi
Service d'Anatomie Pathologique
Sabah Mzabi-Regaya
Service d'Anatomie Pathologique

Abstract

Aim : The Aim of this study is to review clinical data, histological and immunohistochemical findings and prognosis of stromal gastrointestinal tumors.
Methods: A retrospective Study of 32 cases of stromal gastrointestinal tumors diagnosed in the Department of Pathology of Mongi Slim Hospital of Tunis from 1991 à 2004.
Results: The average age of the patients was of 54,4 years, equal for sex. Tumors were essentially gastric (50%) and of the small intestine (37,5%). All the patients had surgical treatment. Gastro-intestinal Stromales Tumors or GIST represent the most frequent stromale tumor with 56,2 % of cases.
Conclusion: After immunohistochimestry study, using CD117, this revision allows better management of GIST. Glivec ® is the standard treatment of advanced GIST.

Keywords:

Gastro-intestinal stromal Tumor, Pathology, Immunohistochimestry

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