Epidemiology of hepatitis C in Tunisia

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Published Mar 5, 2013
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Vol. 91 No. 2 (2013): Issue Feb 2013

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Radhouane Debbeche
Yosra Said
Hanène Ben Temime
Kaouther El Jery
Slim Bouzaïdi
Mohammed Salem
Taoufik Najjar

Abstract

Background: Hepatitis C virus (HCV) infection is one of the main causes of chronic liver disease worldwide.
Aim: To describe epidemiological patterns of hepatitis C in Tunisia.
Methods: Literature review.
Results: In Tunisia, the prevalence of HCV infection is about 0, 7 % in the general population with an increased transmission in the north of the country. Genotype 1b is the most frequent (76 % - 88 %).

Keywords:

Epidemiology, hepatitis C, Tunisia

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References

  1. Lavanchy D. The global burden of hepatitis C. Liver Int 2009;29:74-81.
  2. Shepard CW, Finelli L, Alter MJ. Global epidemiology of hepatitis C virus infection. Lancet Infect Dis 2005;5:558-67.
  3. Afdhal NH. The natural history of hepatitis C. Semin Liver Dis 2004;24:3-8.
  4. Bartosch B, Thimme R, Blum HE, Zoulim F. Hepatitis C virusinduced hepatocarcinogenesis. J Hepatol 2009;51:810-20.
  5. Simmonds P, Bukh J, Combet C, et al. Consensus proposals for a unified system of nomenclature of hepatitis Cvirus genotypes. Hepatology 2005;42:962-73
  6. Desenclos JC. L'infection par le virus de l'hépatite C dans le monde: importance en santé publique, modes de transmission et perspectives. Virologie 2003; 7: 177-91
  7. Bouali M.R, Saïd N, Khediri M.F . Prevalence of hepatitis B and C in more than 56.000 blood donors. J Hepatol 1997; A:172 .
  8. Triki H, Said N, Ben Salah A, et al. Seroepidemiology of hepatitis B, C and delta viruses in Tunisia. Trans R Soc Trop Med Hyg 1997 ; 91:11-4.
  9. Slama H, Mojaat N, Dahri R, Boukef K. Epidemiologic study of anti-HCV antibodies in Tunisian blood donors. Rev Fr Transfus Hemobiol 1991;34:459-64.
  10. Abid S, Fkih S, Khlass B, et al. Screening and confirmation of anti-HCV antibodies in Tunisian blood donors. Transfus Clin Biol 1997;4:221-6.
  11. Hatira SA, Yacoub-Jemni S, Houissa B, et al. Hepatitis C virus antibodies in 34130 blood donors in Tunisian Sahel. Tunis Med 2000;78:101-5.
  12. Gorgi Y, Yalaoui S, Ben Nejma HL, et al. Detection of hepatitis C virus in the general population of Tunisia. Bull Soc Pathol Exot 1998;91:177.
  13. Triki H. Epidemiology of hepatitis B virus, hepatitis C virus and Delta virus in the general population and in liver cirrhosis in Tunisia. Arch InstPasteur Tunis 1994 ;71:403-6.
  14. Ben Khélifa H, Gorgi Y, Sfar I, Hssairi M, Ayed K. Prévalence du portage chronique des virus B, D et C en Tunisie. Résultats d'une enquête Nationale. Xème Congrès National de la Société Tunisienne de Gastroentérologie. Livre des résumés 2006 ; p 30 :A 23
  15. Mejri S, Salah AB, Triki H, Alaya NB, Djebbi A, Dellagi K. Contrasting patterns of hepatitis C virus infection in two regions from Tunisia. J Med Virol 2005 ;76:185-93.
  16. Ben Alaya Bouafif N, Triki H, Mejri S, et al. A case control study to assess risk factors for hepatitis C among a general population in a highly endemic area of northwest Tunisia. Arch Inst Pasteur Tunis 2007; 84:21-7.
  17. Djebbi A, Triki H, Bahri O, et al. Genotypes of hepatitis C virus circulating in Tunisia. Epidemiol Infect 2003; 130:501-5.
  18. Hmida S, Mojaat N, Chaouchi E, et al. HCV antibodies in hemodialyzed patients in Tunisia. Pathol Biol. 1995; 43:581-3.
  19. Jemni S, Ikbel K, Kortas M, et al. Seropositivity to hepatitis C virus in Tunisian haemodialysis patients. Nouv Rev Fr Hematol 1994; 36:349-51.
  20. Hachicha J, Hammami A, Masmoudi H, et al Viral hepatitis C in chronic hemodialyzed patients in southern Tunisia. Prevalence and risk factors. Ann Med Interne 1995;146:295-8.
  21. Sassi F, Gorgi Y, Ayed K, Abdallah TB, Lamouchi A, Maiz HB. Hepatitis C virus antibodies in dialysis patients in Tunisia: a single center study. Saudi J Kidney Dis Transpl 2000 ;11:218-22.
  22. Ayed K, Gorgi Y, Ben Abdallah T, et al .Hepatitis C virus infection in hemodialysis patients from Tunisia: nationalsurvey by serologic and molecular methods. Transplant Proc2003;35:2573-5.
  23. Ben Othman S, Bouzgarrou N, Achour A, Bourlet T, Pozzetto B, Trabelsi A. High prevalence and incidence of hepatitis C virus infections among dialysis patients in the East-Centre of Tunisia. Pathol Biol 2004 ;52:323-7.
  24. Hmaïed F, Ben Mamou M, Dubois M, et al. Determining the source of nosocomial transmission in hemodialysis units in Tunisia by sequencing NS5B and E2 sequences of HCV. J Med Virol2007 ;79:1089-94.
  25. Langar H, Triki H, Gouider E, et al. Blood-transmitted viral infections among haemophiliacs in Tunisia]. Transfus Clin Biol 2005; 12:301-5.
  26. Djebbi A, Bahri O, langar H, Sadraoui A, Mejri S, Triki H. Genetic variability of genotype 1 hepatitis C virus isolates from Tunisian haemophiliacs. New Microbiol 2008; 31: 473-81.
  27. Coursaget P, Simpson B, El Goulli N, Ben Khelifa H, Kastally R. Hepatitis C core antibody detection in acute hepatitis and cirrhosis patients from Tunisia. Pathol Biol 1992; 40: 646-8.
  28. Coursaget P, Leboulleux D, Gharbi Y, et al. Etiology of acute sporadic hepatitis in adults in Senegal and Tunisia. Scand J Infect Dis 1995; 27:9-11.
  29. Triki H. Epidémiologie des virus des hépatites B, C et Delta dans la population générale et les cirrhoses hépatiques en Tunisie. Arch Inst Pasteur Tunis 1994 ; 71 :403-6.