Peripancreatic sporadic gastrinoma

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Published Oct 1, 2010
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Vol. 88 No. 10 (2010): Issue Oct 2010

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Wael Rebai
Rachid Ksantini
Faouzi Chebbi
Department of Surgery
Amin Makni
Sofiene Ayadi
Amin Daghfous
Fadhel Fterich
Haykal Bedioui
Adel Ammous
Mohamed Jouini
Montasser Kacem
Zoubeir Ben Safta

Abstract

Background : The peri-pancreatic sporadic gastrinoma represents a paradigm of digestive endocrinology. It was originally an abnormal secretion of gastrin fits the syndrome Zollinger-Ellison.
Aim: The objective of our work is to clarify the diagnostic strategy and therapeutic conduct of gastrinoma.
Case : We report the case of a patient aged 42 years, hospitalized for bleeding duodenal ulcer, revealed a Zollinger-Ellison syndrome. The different explorations have shown that it was a primitive péripancréatique sporadic gastrinoma. In surgery, we discover a rétropancréatique tumor associated to a stenosis post-bulbar ulcer. It was conducted a enucleation of the tumor with vagotomie troncular and gastroenteroanastomosis. The forecast was favourable with normalization of the values of gastrinémie.
Conclusion : The sporadic gastrinoma is rare, its emphasis is increasingly being facilitated by the technology of modern medical imaging, belonging to a polyendocrinopathie must be systematic search. Treatment of pancreatic gastrinoma is multidisciplinary. Surgery is the only cure for this disease.

Keywords:

Gastrinoma, Zollinger-Ellison

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