Objectif: Évaluer l’effet de six semaines d’entraînement par intervalles à haute intensité (EIHI) et de supplémentation en L-Arginine sur les taux d’interleukine-6 (IL-6) et la composition corporelle chez des hommes iraniens adultes entraînés.
Méthodes: Cette étude expérimentale était réalisée en tant qu’intervention avec une conception pré-test/post-test dans trois groupes expérimentaux et un groupe témoin. Quarantehuit jeunes hommes de la province de Qazvin (Iran) étaient sélectionnés volontairement sur la base d’un échantillonnage de commodité. Les participants étaient répartis au hasard en quatre groupes (12 participants dans chaque groupe): «EIHI»; «Supplémentation en L-Arginine»; «EIHI + Supplémentation L-Arginine» et «EIHI + placebo». À 7 heures du matin, lorsque le taux d’inflammation était à son plus bas, un échantillon de sang était prélevé, et l’indice de masse corporelle (IMC), le pourcentage de masse graisse (%MG), et la masse maigre (MM) étaient déterminés. L’analyse de l’IL-6 a été effectuée à l’aide du dispositif STATE FAX et de la méthode ELISA. Les sessions d’entraînement étaient menées pendant six semaines consécutives, trois sessions par semaine. L’analyse de covariance et le test post hoc de Bonferroni étaient utilisés pour analyser les données.
Résultats: i) Il n’y avait pas de différences significatives entre les groupes en termes d’IMC, de %MG ou de MM. ii) Il y avait une différence significative dans les taux d’IL-6 entre les groupes (p < 0,05), de sorte que les niveaux inflammatoires dans les groupes «EIHI + Supplémentation en L-Arginine» et «EIHI + placebo» étaient inférieurs au «EIHI» (0,002 et <0,001, respectivement) et «Supplémentation en L-Arginine» (<0,001 et <0,001, respectivement). L’EIHI «semble» réduire le niveau d’inflammation.
Conclusion: L’EIHI n’a eu aucun effet significatif sur les indices de la composition corporelle. Les taux d’IL-6 ont diminué après six semaines d’EIHI et de supplémentation en L-Arginine. La concentration d’IL-6 dans les groupes «EIHI + Supplémentation en L-Arginine» et «EIHI + placebo» était inférieur à celle du groupe témoin (cad «EIHI») et du groupe témoin supplémenté (cad «Supplémentation en L-Arginine»).

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