La tunisie Medicale - 2022 ; Vol 100 ( n°06 ) : 477-480
[ 462 times seen ]
Summary

Introduction: Several studies examined the effects of creatine monohydrate supplementation on renal function, but no previous study has investigated its effects on kidney stones in humans.
Observation: A renal ultrasound in a healthy young athlete (without a known renal morphological anomaly, normal kidney function, normal phospholipid and uric acid data) revealed a kidney stone of 11 mm in the lower right calyx. Extracorporeal shock wave lithotripsy was applied in order to break the down stone. Twentyone days later, a follow-up renal ultrasound showed the absence of stones in the kidney. One week later, the athlete started creatine monohydrate supplementation for two months. Fourteen months after stopping creatine monohydrate supplementation, a third renal ultrasound confirmed the absence of stones in the kidney.
Conclusion: Two months of creatine monohydrate supplementation in an athlete with a history of kidney stones could not be associated with kidney stone recurrence in the long run.

Key - Words
Article
Reference
  1. De Souza E Silva A, Pertille A, Reis Barbosa CG, Aparecida de Oliveira Silva J, de Jesus DV, Ribeiro AGSV, et al. Effects of creatine supplementation on renal function: a systematic review and meta-analysis. J Ren Nutr. 2019;29(6):480-489.
  2. Butts J, Jacobs B, Silvis M. Creatine use in sports. Sports Health.2018;10(1):31-34.
  3. Kreider RB, Kalman DS, Antonio J, Ziegenfuss TN, Wildman R, Collins R, et al International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017;14(1):18.
  4. Cancela P, Ohanian C, Cuitiño E, Hackney AC. Creatine supplementation does not affect clinical health markers in football players. Br J Sports Med. 2008;42(9):731- 5..
  5. Gualano B, Ferreira DC, Sapienza MT, Seguro AC, Lancha AH, Jr. Effect of short-term high-dose creatine supplementation on measured GFR in a young man with a single kidney. Am J Kidney Dis. 2010;55(3):e7-9.
  6. Gualano B, Ugrinowitsch C, Novaes RB, Artioli GG, Shimizu MH, Seguro AC, et al. Effects of creatine supplementation on renal function: a randomized, double- blind, placebo-controlled clinical trial. Eur J Appl Physiol. 2008;103(1):33-40.
  7. Gagnier JJ, Kienle G, Altman DG, Moher D, Sox H, Riley D, et al. The CARE guidelines: consensus-based clinical case reporting guideline development. Glob Adv Health Med. 2013 Sep;2(5):38-43.
  8. Farquhar WB, Zambraski EJ. Effects of creatine use on the athlete’s kidney. Curr Sports Med Rep. 2002;1(2):103-6.
  9. Davani-Davari D, Karimzadeh I, Ezzatzadegan-Jahromi S, Sagheb MM. Potential adverse effects of creatine supplement on the kidney in athletes and bodybuilders. Iran J Kidney Dis. 2018;12(5):253-60.
  10. Carvalho APPF, Molina GE, Fontana KE. Creatine supplementation associated with resistance training does not alter renal and hepatic functions. Rev Bras de Medicina do Esporte. 2011;17(4):237-41.
  11. Kreider RB, Melton C, Rasmussen CJ, Greenwood M, Lancaster S, Cantler EC, et al. Long-term creatine supplementation does not significantly affect clinical markers of health in athletes. Mol Cell Biochem. 2003;244(1-2):95-104.
  12. Lugaresi R, Leme M, de Salles Painelli V, Murai IH, Roschel H, Sapienza MT, et al. Does long-term creatine supplementation impair kidney function in resistance- trained individuals consuming a high-protein diet? J Int Soc Sports Nutr. 2013;10(1):26.
  13. Gualano B, de Salles Painelli V, Roschel H, Lugaresi R, Dorea E, Artioli GG, et al. Creatine supplementation does not impair kidney function in type 2 diabetic patients: a randomized, double-blind, placebo-controlled, clinical trial. Eur J Appl Physiol. 2011;111(5):749-56.
  14. Taner B, Aysim O, Abdulkadir U. The effects of the recommended dose of creatine monohydrate on kidney function. NDT Plus. 2011;4(1):23-4.
  15. Thorsteinsdottir B, Grande JP, Garovic VD. Acute renal failure in a young weight lifter taking multiple food supplements, including creatine monohydrate. J Ren Nutr. 2006;16(4):341-5.
  16. Barisic N, Bernert G, Ipsiroglu O, Stromberger C, Muller T, Gruber S, et al. Effects of oral creatine supplementation in a patient with MELAS phenotype and associated nephropathy. Neuropediatrics. 2002;33(3):157-61.
  17. Kuehl K, Goldberg L, Elliot D. Renal insufficiency after creatine supplementation in a college football athlete. Med Sci Sports Exerc. 1998;30(5):235.
  18. Pritchard NR, Kalra PA. Renal dysfunction accompanying oral creatine supplements. Lancet. 1998;351(9111):1252-3.
  19. Van der Merwe J, Brooks NE, Myburgh KH. Three weeks of creatine monohydrate supplementation affects dihydrotestosterone to testosterone ratio in college-aged rugby players. Clin J Sport Med. 2009;19(5):399-404.
  20. Andriole G, Bruchovsky N, Chung LW, Matsumoto AM, Rittmaster R, Roehrborn C, et al. Dihydrotestosterone and the prostate: the scientific rationale for 5alpha- reductase inhibitors in the treatment of benign prostatic hyperplasia. J Urol. 2004;172(4 Pt 1):1399-403.
Login
E-mail :
Password :
Remember Me Forgot password? Sign UP
Archives
2022
January
February
March
April
May
June
July
August
September
October
November
December
Keywords most used
Tunisia treatment Child diagnosis surgery prognosis Children Crohn’s disease epidemiology Risk factors Breast cancer Cancer screening obesity Quality of life
Newsletter
Sign up to receive our newsletter
E-mail :
Stay in Touch
Join Us! !