La tunisie Medicale - 2022 ; Vol 100 ( n°04 ) : 295-302
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Les deux principales fonctions du poumon sont la fonction respiratoire, qui correspond à la mécanique ventilatoire et les échanges gazeux, et les fonctions non respiratoires, métaboliques, immunologiques et endocriniennes. Le vieillissement pulmonaire est secondaire à l’altération, liée à l’âge, d’une ou plusieurs de ces fonctions. Le tabagisme accélère le vieillissement pulmonaire et touche les fonctions biologiques, structurelles, respiratoires et non respiratoires. Ces changements contribuent au développement de maladies pulmonaires chroniques et prédisposent aux infections pulmonaires chez les personnes âgées. La connaissance de ces changements est très utile pour une meilleure prise en charge des personnes âgées. La santé pulmonaire dans le vieillissement peut être améliorée par des stratégies qui ralentissent le déclin de la fonction pulmonaire lié à l’âge en agissant sur les paramètres environnementaux. Il est également possible d’améliorer le développement pulmonaire chez l’enfant et de renforcer la résistance des poumons aux défis environnementaux et donc au vieillissement pulmonaire extrinsèque.

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