La tunisie Medicale - 2021 ; Vol 99 ( n°06 ) : 623-631
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Background: Chronic obstructive pulmonary disease (COPD) is a chronic lung disease with a multi-systemic impact that can be complicated by psycho-affective disorders.
Aim: To determinethe frequency of anxiety and depression in patients followed for stable COPD in a university hospital-center in Tunisand to determine the predictors of their onset.
Methods: This was an analytical cross-sectional studyof patients followed for stable COPD at the pulmonology department of the Mongi Slim La Marsa Hospital. The symptoms of COPD were assessed by the Chronic obstructive pulmonary disease Assessment Test (CAT), its severity by the GOLD 2020 classification and the screening of psycho-affective disorders by the HAD scale.
Results: One hundred and three patients were enrolled, with an average age of 64 years. The prevalence of anxiety was 44.7% and that of depression was 33.9%with 26.2% of patients with a major depressive episode. In multivariate analysis by binary logistic regression, the highest values of CAT score were associated with anxiety, depression, and the onset of a major depressive episode. Other factors associated with anxiety and the onset of a major depressive episode were associated heart rhythm disorders and the lowest BMI values. In addition, the female gender was associated with the onset of a major depressive episode.
Conclusion: Anxiety and depression are common in Tunisian patients with COPD, hence the interest of their systematic screening.

Key - Words
  1. 1- Global initiative for chronic obstructive lung disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease. 2020 report. Fontana, WI, USA2020. https://goldcopd. org/wpcontent/uploads/2019/11/GOLD-2020-REPORT-ver1. 0wms. pdf 2- Polatli M, Ben Kheder A, Wali S, et al. Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: the BREATHE study. Respir Med 2012;106:S75– S85. 3- Sulieman Terkawi A, Tsang S, Jumaan AlKahtani G, et al. Development and validation of Arabic version of the Hospital Anxiety and Depression Scale. Saudi J Anaesth 2017;11 (Suppl 1) :S11–S18. 4- Turan O, Yemez B, Itil O. The effects of anxiety and depression symptoms on treatment adherence in COPD patients. Prim Health Care Res Dev 2014;15 (3) :244-51. 5- Munari AB, Gulart AA, Dos Santos K, Venâncio RS, Karloh M, Mayer AF. Modified Medical Research Council Dyspnea Scale in GOLD Classification Better Reflects Physical Activities of Daily Living. Respir Care 2018;63 (1) :77-85. 6- Gupta N, Pinto LM, Morogan A, Bourbeau J. The COPD assessment test: a systematic review. ERJ 2014;44:873-84. 7- Maoua M, El Maalel O, Abdelghani A, et al. Impact de la BPCO sur la qualité de vie et l’état de santé mentale chez cent patients tunisiens. Rev Pneumol clin2014;70:195-202. 8- Xiao T, Qiu H, Chen Y, et al. Prevalence of anxiety and depression symptoms and their associated factors in mild COPD patients from community settings, Shanghai, China: a cross-sectional study. BMC Psychiatry 2018;18:89. 9- Uchmanowicz I, Jankowska-Polanska B, Motowidlo U, Uchmanowicz B, Chabowski M. Assessment of illness acceptance by patients with COPD and the prevalence of depression and anxiety in COPD. Int J Chron Obstruct Pulmon Dis 2016;11:963-70. 10- Schüz N, Walters J, Cameron-Tucker H, Scott J, Wood-Baker R, Walters EH. Patient Anxiety and Depression Moderate the Effects of Increased Self-management Knowledge on Physical Activity: A Secondary Analysis of a Randomised Controlled Trial on Health-Mentoring in COPD. COPD 2015;00:1–8. 11- Engum A. The role of depression and anxiety in onset of diabetes in a large population-based study. J Psychosom Res 2007;62:31–8. 12- Ninot G. L’anxiété et la dépression associées à la BPCO ; une revue de la question. Rev Mal Respir 2011;28:729-48. 13- Maurer J, Rebbapragada V, Borson S, et al. Anxiety and depression in COPD: current understanding, unanswered questions, and research needs. Chest2008;134:43S-56S. 14- Jones PW, Baveystock CM, Littlejohns P. Relationships between LA TUNISIE MEDICALE - 2021 ; Vol 99 (n°06) 631 general health measured with the sickness impact profile and respiratory symptoms, physiological measures, and mood in patients with chronic airflow limitation. Am J Respir Crit Care Med 1989;140:1538-43. 15- Laurin C, Lavoie KL, Bacon SL, et al. Sex differences in the prevalence of psychiatric disorders and psychological distress in patients with COPD. Chest2007;132:148-55. 16- Ninot G, Fortes M, Poulain M, et al. Gender difference in coping strategies among patients enrolled in an inpatient rehabilitation program. Heart Lung 2006;35:130-6. 17- Gordon CS, Waller JW, Cook RM, Cavalera SL, Lim WT, Osadnik CR. Effect of Pulmonary Rehabilitation on Symptoms of Anxiety and Depression in COPD: A Systematic Review and Meta-Analysis. Chest 2019;156 (1) :80-91.
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treatment Child diagnosis surgery prognosis Tunisia Children Crohn’s disease Breast cancer Cancer screening epidemiology Ulcerative colitis mammography obesity
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